Möbius Syndrome: Misoprostol Use and Speech and Language Characteristics

Möbius Syndrome: Misoprostol Use and Speech and Language Characteristics

Author Guedes, Zelita Caldeira Ferreira Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract Introduction Möbius syndrome (MS; VI and VII palsy) is a rare disease that in Brazil has a great frequency because of the use of misoprostol during pregnancy. Objective Verify if the speech and language performance of children with MS whose mothers reported use of misoprostol (Cytotec, Pfizer, Connecticut, USA) are different from the performance of children of mothers who did not report use. Methods The stomatognathic system beyond receptive and expressive language and speech was evaluated in children with MS, and their mothers were questioned whether they used misoprostol during the pregnancy. Results During the interview, 61.11% of mothers reported that they took misoprostol during the pregnancy. Most of the subjects (83.3%) whose mothers took misoprostol presented bilateral palsy beyond bad mobility of the tongue (90.9%) and speech disorders (63.6%). Conclusion The number of mothers who took misoprostol without knowing the risk for MS was great. The lack of facial expressions and speech disorders were common characteristics of the individuals with MS, whether the mothers took misoprostol during the pregnancy or not.
Keywords misoprostol
speech disorders
rehabilitation of speech and language disorders
Language English
Date 2014-09-01
Published in International Archives of Otorhinolaryngology. Fundação Otorrinolaringologia, v. 18, n. 3, p. 239-243, 2014.
ISSN 1809-4864 (Sherpa/Romeo)
Publisher Fundação Otorrinolaringologia
Extent 239-243
Origin http://dx.doi.org/10.1055/s-0033-1363466
Access rights Open access Open Access
Type Article
SciELO ID S1809-48642014000300239 (statistics in SciELO)
URI http://repositorio.unifesp.br/handle/11600/8566

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