Dental anomalies in children submitted to antineoplastic therapy

Dental anomalies in children submitted to antineoplastic therapy

Author Carrillo, Camila Merida Google Scholar
Corrêa, Fernanda Nahás Pires Google Scholar
Lopes, Nilza Nelly Fontana Autor UNIFESP Google Scholar
Fava, Marcelo Google Scholar
Odone Filho, Vicente Google Scholar
Institution Universidade de São Paulo (USP)
São Leopoldo Mandic Campinas School of Dentistry
Universidade Federal de São Paulo (UNIFESP)
Universidade Estadual Paulista (UNESP)
Abstract Cancer is the third most frequent cause of death in children in Brazil. Early diagnosis and medical advances have significantly improved treatment outcomes, which has resulted in higher survival rates and the management of late side effects has become increasingly important in caring for these patients. Dental abnormalities are commonly observed as late effects of antineoplastic therapy in the oral cavity. The incidence and severity of the dental abnormalities depend on the child's age at diagnosis and the type of chemotherapeutic agent used, as well as the irradiation dose and area. The treatment duration and aggressivity should also be considered. Disturbances in dental development are characterized by changes in shape, number and root development. Enamel anomalies, such as discoloration, opacities and hypoplasia are also observed in these patients. When severe, these abnormalities can cause functional and esthetic sequelae that have an impact on the children's and adolescents' quality of life. General dentists and pediatric dentists should understand these dental abnormalities and how to identify them aiming for early diagnosis and appropriate treatment.
Keywords Tooth Abnormalities
Drug/Radiotherapy
Cancer
Child
Language English
Date 2014-06-01
Published in Clinics. Faculdade de Medicina / USP, v. 69, n. 6, p. 433-437, 2014.
ISSN 1807-5932 (Sherpa/Romeo, impact factor)
1980-5322 (Sherpa/Romeo, impact factor)
Publisher Faculdade de Medicina / USP
Extent 433-437
Origin http://dx.doi.org/10.6061/clinics/2014(06)11
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000338440500011
SciELO ID S1807-59322014000600433 (statistics in SciELO)
URI http://repositorio.unifesp.br/handle/11600/8396

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