Author |
Pereira, Daniele Freitas
![]() ![]() Natour, Jamil ![]() ![]() Buosi, Ana Letícia Pirozzi ![]() ![]() Ferreira, Fernando Bernardes Maia Diniz ![]() ![]() Fernandes, Artur da Rocha Correa ![]() ![]() Furtado, Rita Nely Vilar ![]() ![]() |
Institution | Universidade Federal de São Paulo (UNIFESP) |
Abstract | OBJECTIVE: This study compares the clinical, ultrasonography, radiography, and laboratory outcomes of painless and painful chronic synovitis in patients with established rheumatoid arthritis. METHODS: This cross-sectional study involved 60 patients with rheumatoid arthritis and synovitis in the metacarpophalangeal joints; 30 of the patients did not experience pain, and 30 had experienced pain for at least 6 months prior to the study. The radiocarpal, distal radioulnar, and metacarpophalangeal joints were evaluated using the ultrasound gray scale, power Doppler, and radiography. Past and present clinical and laboratory findings were also evaluated. RESULTS: There were no statistically significant differences between the groups for most of the outcomes. The group with pain scored worse on the disease activity indices (e.g., DAS 28 and SDAI), function questionnaires (HAQ and Cochin), and pinch strength test. A logistic regression analysis revealed that the use of an immunobiological agent was associated with a 3-fold greater chance of belonging to the group that experienced pain. The painless group had worse erosion scores in the second and fifth metacarpophalangeal with odd ratios (ORs) of 6.5 and 3.5, respectively. The painless group had more cartilage with grade 4 damage in the third metacarpophalangeal. CONCLUSIONS: The rheumatoid arthritis patients with both painless and painful synovitis exhibited similar disease histories and radiographic and ultrasound findings. However, the ultrasonography evaluation revealed worse scores in the second and fifth metacarpophalangeal of the synovitis patients who did not experience pain. |
Keywords |
Rheumatoid Arthritis
Synovitis Pain Ultrasound Radiographic |
Language | English |
Sponsor | Fundacao de Amparo a Pesquisa do Estado de Sao Paulo UNIFESP community Hospital do Servidor Publico Estadual (IAMSPE) |
Grant number |
|
Date | 2014-02-01 |
Published in | Clinics. Faculdade de Medicina / USP, v. 69, n. 2, p. 93-100, 2014. |
ISSN | 1807-5932 (Sherpa/Romeo, impact factor) 1980-5322 (Sherpa/Romeo, impact factor) |
Publisher | Faculdade de Medicina / USP |
Extent | 93-100 |
Origin |
|
Access rights | Open access ![]() |
Type | Article |
Web of Science ID | WOS:000331931800004 |
SciELO ID | S1807-59322014000200093 (statistics in SciELO) |
URI | http://repositorio.unifesp.br/handle/11600/8230 |
Name:
S1807-59322014000200093.pdf
Size: 911.8Kb Format: PDF Description: |
Open file |