Spitz nevus and Reed nevus

Alternative title Nevo de Spitz e nevo de Reed
Author Yoradjian, Alessandra Google Scholar
Enokihara, Mílvia Maria Simões e Silva Autor UNIFESP Google Scholar
Paschoal, Francisco Macedo Autor UNIFESP Google Scholar
Institution ABC School of Medicine
Universidade Federal de São Paulo (UNIFESP)
Abstract Spitz and Reed nevi, also called spindle and/or epithelioid cell nevi, are a special group of melanocytic lesions due to their peculiar clinical, dermoscopic and histopathological features. The study of these nevi is of great interest because both their nomenclature and classification are still a matter of discussion. Most importantly, the difficulty to differentiate them from melanoma can lead to inadequate therapies. In this context, dermoscopy, a link between clinical and anatomopathological examinations, appears as a helpful diagnostic tool whose accuracy can reach 93%. Borderline lesions are still a great challenge and object of research, including molecular studies. The present study explores the relevant characteristics of these nevi, with emphasis on dermoscopic findings, aiming at understanding their natural history, as well as discussing treatment and patient follow-up.

Os nevos de Spitz e de Reed, ou também chamados nevos de células fusiformes e/ou epitelióides, formam um grupo especial de lesões melanocíticas, por suas características peculiares, tanto clínicas como dermatoscópicas e histopatológicas. Torna-se grande o interesse no estudo desses nevos, pois tanto a nomenclatura como a classificação ainda são motivos de debate e, sobretudo, a dificuldade de diferenciação com o melanoma pode gerar condutas terapêuticas inadequadas. Neste contexto, surge a dermatoscopia, elo entre o exame clínico e o anatomopatológico, como método diagnóstico auxiliar importante cuja acurácia pode chegar a 93%. A grande dificuldade ainda são as lesões borderline, motivo de pesquisas, incluindo estudos moleculares. O presente estudo aborda os aspectos relevantes das características destes nevos, com ênfase nos achados dermatoscópicos, buscando o entendimento da sua história natural, além da discussão quanto ao tratamento e seguimento dos pacientes.
Keywords dermoscopy
melanoma
nevus
epithelioid and spindle cell
dermoscopia
melanoma
nevo de células epitelióides e fusiformes
Language English
Date 2012-06-01
Published in Anais Brasileiros de Dermatologia. Sociedade Brasileira de Dermatologia, v. 87, n. 3, p. 349-359, 2012.
ISSN 0365-0596 (Sherpa/Romeo, impact factor)
Publisher Sociedade Brasileira de Dermatologia
Extent 349-359
Origin http://dx.doi.org/10.1590/S0365-05962012000300001
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000305472200001
SciELO ID S0365-05962012000300001 (statistics in SciELO)
URI http://repositorio.unifesp.br/handle/11600/7190

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