Laryngeal sequelae of recurrent respiratory papillomatosis surgery in children

Laryngeal sequelae of recurrent respiratory papillomatosis surgery in children

Author Hermann, Juliana Sato Autor UNIFESP Google Scholar
Pontes, Paulo Autor UNIFESP Google Scholar
Weckx, Luc Louis Maurice Autor UNIFESP Google Scholar
Fujita, Reginaldo Raimundo Autor UNIFESP Google Scholar
Avelino, Melissa Ameloti Gomes Autor UNIFESP Google Scholar
Pignatari, Shirley Shizue Nagata Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract OBJECTIVE: To evaluate laryngeal sequelae from surgical treatment of recurrent respiratory papillomatosis in children, as well as associated risk factors. METHODS: Case-control study. Medical record data analysis of 50 children with recurrent respiratory papillomatosis, divided into two groups: with and without laryngeal sequelae. The group of patients with laryngeal sequelae was compared to those without sequelae in regard to the onset of disease, age at first surgery, number and frequency of surgeries, disease stage, and type of surgery (CO2 laser, cold forceps). RESULTS: 23 patients (46%) sustained laryngeal sequelae. The most frequent sequela was anterior commissure synechia (17 patients [34%]), followed by glottic stenosis (six patients [12%]). There was no statistically significant difference between groups with and without laryngeal sequelae regarding the disease onset (p = 0.93), age at first surgery (p = 0.68), number of surgeries (p = 0.22), annual frequency of surgery (p = 0.93), presence of papilloma in anterior (p = 0.430) or posterior commissure (p = 0.39), and type of surgery (p = 0.27). The Derkay anatomical score (a staging system that assesses the extent of the disease in the aerodigestive tract) was significantly higher in the laryngeal sequelae group (p = 0.04). CONCLUSION: Laryngeal sequelae are a frequent complication of recurrent respiratory papillomatosis surgical treatment in children, particularly anterior commissure synechiae and glottic stenosis. Advanced stages are associated with increased risk of laryngeal sequelae after surgery.
Keywords Papilloma
postoperative complications
papillomavirus infections
Language English
Date 2012-04-01
Published in HERMANN, Juliana Sato et al . Laryngeal sequelae of recurrent respiratory papillomatosis surgery in children. Rev. Assoc. Med. Bras., São Paulo , v. 58, n. 2, p. 204-208, abr. 2012
ISSN 0104-4230 (Sherpa/Romeo, impact factor)
Publisher Associação Médica Brasileira
Extent 204-208
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000302926900018
SciELO ID S0104-42302012000200016 (statistics in SciELO)

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