Brazilian plants with possible action on the Central Nervous System: a study of historical sources from the 16th to 19th century

Brazilian plants with possible action on the Central Nervous System: a study of historical sources from the 16th to 19th century

Author Giorgetti, Melina Autor UNIFESP Google Scholar
Rossi, Lucia Google Scholar
Rodrigues, Eliana Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Instituto de Botânica de São Paulo
Abstract Ethnopharmacological research when grounded on historic literature has for its objective retrieving traditional knowledge compiled throughout history by early cultures. The current study has used literature from the 16th to the 19th centuries to assess reports that include accounts of Brazil's native plants, with possible reports of disorders of the Central Nervous System (CNS). Visits were paid to 27 institutions located in four Brazilian states. This resulted in raising 529 publications, out of which 65 were read, revealing that 33 of them contained reports of plants exerting effects on CNS ailments. These plants' scientific names underwent an updating process. The updating process resulted in 788 species names (129 correct scientific names and their 659 synonyms) out of which 66 hold current ethnopharmacology, pharmacology studies and/or patent application. Coincidences among past and present data have been observed in 46 cases. Only three of them carried applications for patents all of which coincided with past uses. There have hardly been any studies whatsoever throughout the centuries for many of the species currently being studied. Although of very seldom use, research in ethnopharmacology and historic literature can be promising tools for the selecting of new pharmaco products, further to contributing with retrieving traditional knowledge.
Keywords Ethnopharmacology
historic literature
Central Nervous System
medicinal plants
traditional knowledge
Language English
Sponsor Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Associação Fundo de Incentivo à Pesquisa (AFIP)
Grant number CNPq: 133440/2006-0
FAPESP: 06/56240-6
Date 2011-06-01
Published in Revista Brasileira de Farmacognosia. Sociedade Brasileira de Farmacognosia, v. 21, n. 3, p. 537-555, 2011.
ISSN 0102-695X (Sherpa/Romeo, impact factor)
Publisher Sociedade Brasileira de Farmacognosia
Extent 537-555
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000292919800029
SciELO ID S0102-695X2011000300029 (statistics in SciELO)

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