Is allergic rhinitis a trivial disease?

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dc.contributor.author Solé, Dirceu [UNIFESP]
dc.contributor.author Camelo-Nunes, Inês Cristina [UNIFESP]
dc.contributor.author Wandalsen, Gustavo Falbo [UNIFESP]
dc.contributor.author Rosario Filho, Nelson Augusto
dc.contributor.author Sarinho, Emanuel C
dc.date.accessioned 2015-06-14T13:42:51Z
dc.date.available 2015-06-14T13:42:51Z
dc.date.issued 2011-01-01
dc.identifier http://dx.doi.org/10.1590/S1807-59322011000900012
dc.identifier.citation Clinics. Faculdade de Medicina / USP, v. 66, n. 9, p. 1573-1577, 2011.
dc.identifier.issn 1807-5932
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/6243
dc.description.abstract BACKGROUND: Asthma and rhinitis often coexist, which potentially increases the disease severity and can negatively impact a patients' quality of life. However, there are few reports based on data obtained from the International Study of Asthma and Allergies in Childhood examining asthma severity in combination with rhinitisrelated symptoms. OBJECTIVE: To demonstrate whether current rhinitis and current rhinoconjunctivitis are associated with the development of asthma or its increasing severity in Brazilian adolescents. METHODS: The prevalence of current asthma was correlated with the prevalence of current rhinitis and current rhinoconjunctivitis in adolescents (13 to 14 year olds) from 16 Brazilian centers (based on Spearman's rank correlation index). The influence of current rhinitis and current rhinoconjunctivitis on asthma presentation was also evaluated using the chi-squared test and was expressed as odds ratios with 95% confidence intervals (95%CI). RESULTS: A significant positive correlation was observed between the prevalence of current asthma and current rhinitis (rs = 0.82; 95%CI: 0.60-0.93, p< 0.0001) and between the prevalence of current asthma and current rhinoconjunctivitis (rs = 0.75; 95%CI: 0.47-0.89, p < 0.0001). Current rhinitis was associated with a significantly increased risk of current asthma and of more severe asthma. Similar results were observed for current rhinoconjunctivitis. CONCLUSION: In this epidemiologic study of Brazilian adolescents, the presence of current rhinitis and current rhinoconjunctivitis was associated with a high risk of developing asthma and increased asthma severity. The mutual evaluation of rhinitis and asthma is necessary to establish an adequate treatment plan. en
dc.format.extent 1573-1577
dc.language.iso eng
dc.publisher Faculdade de Medicina / USP
dc.relation.ispartof Clinics
dc.rights Acesso aberto
dc.subject Epidemiology en
dc.subject Asthma en
dc.subject Rhinitis en
dc.subject Rhinoconjunctivitis en
dc.subject ISAAC en
dc.title Is allergic rhinitis a trivial disease? en
dc.type Artigo
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.contributor.institution Federal University of Paraná Department of Pediatrics
dc.contributor.institution Federal University of Pernambuco Department of Pediatrics
dc.description.affiliation Federal University of São Paulo Department of Pediatrics
dc.description.affiliation Federal University of Paraná Department of Pediatrics
dc.description.affiliation Federal University of Pernambuco Department of Pediatrics
dc.description.affiliationUnifesp UNIFESP, Department of Pediatrics
dc.identifier.file S1807-59322011000900012.pdf
dc.identifier.scielo S1807-59322011000900012
dc.identifier.doi 10.1590/S1807-59322011000900012
dc.description.source SciELO
dc.identifier.wos WOS:000297498400012



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