Does the Capsule Interfere with Performance of Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry for Identification of Cryptococcus neoformans and Cryptococcus gattii?

Does the Capsule Interfere with Performance of Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry for Identification of Cryptococcus neoformans and Cryptococcus gattii?

Author Thomaz, Danilo Y. Google Scholar
Grenfell, Rafaella C. Autor UNIFESP Google Scholar
Vidal, Monica S. M. Google Scholar
Giudice, Mauro C. Google Scholar
Del Negro, Gilda M. B. Google Scholar
Juliano, Luiz Autor UNIFESP Google Scholar
Benard, Gil Google Scholar
de Almeida Junior, Joao N. Google Scholar
Abstract We described the impact of the capsule size for Cryptococcus neoformans and Cryptococcus gattii identification at the species level by Bruker matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS). After experimental capsule size modulation, we observed that reducing the capsule size resulted in improved identification by Bruker MALDI-TOF MS across all of the reference strains analyzed.
xmlui.dri2xhtml.METS-1.0.item-coverage Washington
Language English
Date 2016
Published in Journal Of Clinical Microbiology. Washington, v. 54, n. 2, p. 474-477, 2016.
ISSN 0095-1137 (Sherpa/Romeo, impact factor)
Publisher Amer Soc Microbiology
Extent 474-477
Origin https://doi.org/10.1128/JCM.02635-15
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000369155100038
URI https://repositorio.unifesp.br/handle/11600/58641

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