Plasma Leptin and Premenstrual Syndrome: A Review

Plasma Leptin and Premenstrual Syndrome: A Review

Author Martinho Nicolau, Zaira Fernanda Autor UNIFESP Google Scholar
Bezerra, Andreia Gomes Autor UNIFESP Google Scholar
Polesel, Daniel Ninello Autor UNIFESP Google Scholar
Andersen, Monica Levy Autor UNIFESP Google Scholar
Tufik, Sergio Autor UNIFESP Google Scholar
Hachul, Helena Autor UNIFESP Google Scholar
Abstract Importance Premenstrual syndrome (PMS) is characterized by physical and psychological symptoms in the luteal phase. Leptin can influence PMS as it acts on the hypothalamic-pituitary-gonadal axis. Objective The aim of this study was to evaluate data in the literature about the profile of plasma leptin in women with PMS. Evidence Acquisition We performed a search of databases using both descriptors. Three studies were identified. They included 181 participants. Two of these studies found higher leptin levels in women with PMS. Results Conflicting results were found regarding the leptin levels in the luteal phase and the correlation between leptin, estradiol, and progesterone levels. Conclusions and Relevance Leptin could have a role in the pathophysiology of PMS and indicate degree of severity of PMS. Future studies on the role of leptin in PMS are needed. Target Audience Obstetricians and gynecologists, family physicians. Learning Objectives After completing this activity, the learner should be better able to describe the correlation between women with PMS and leptin concentration, analyze if there is a difference between leptin concentration in the phases of the menstrual cycle, and foresee the future clinical applicability of leptin's concentration in women with PMS.
xmlui.dri2xhtml.METS-1.0.item-coverage Philadelphia
Language English
Date 2017
Published in Obstetrical & Gynecological Survey. Philadelphia, v. 72, n. 11, p. 659-662, 2017.
ISSN 0029-7828 (Sherpa/Romeo, impact factor)
Publisher Lippincott Williams & Wilkins
Extent 659-662
Access rights Closed access
Type Article
Web of Science ID WOS:000416005500018

Show full item record


File Size Format View

There are no files associated with this item.

This item appears in the following Collection(s)




My Account