Zika virus and the eye

Author Freitas, Bruno de Paula Autor UNIFESP Google Scholar
Ventura, Camila V. Autor UNIFESP Google Scholar
Maia, Mauricio Autor UNIFESP Google Scholar
Belfort, Rubens, Jr. Autor UNIFESP Google Scholar
Abstract Purpose of review The aim of this study was to review the ocular findings related to the Zika virus (ZIKV) based on the main studies published to date, describe the patterns of the lesions and risk factors, and identify the public health implications and scientific importance of this emerging disease. Recent findings In most studies, the ZIKV seems related to congenital ocular lesions and most mothers reported mild symptoms during the first pregnancy trimester. Five fundus patterns were seen most often: macular chorioretinal atrophy, chorioretinal atrophy elsewhere, focal pigmentary changes in the macular region, optic nerve abnormalities and combined types. A few studies have suggested that the ZIKV might damage the anterior segment of these babies' eyes. Few reports have described the ocular complications seen in adults during the acute infection, including conjunctivitis, iridocyclitis and chorioretinitis. Summary Infants with congenital Zika syndrome might have vision-threatening fundus abnormalities. Although the full spectrum of ocular lesions caused by the ZIKV infection is not yet determined, a distinctive new disease has been observed. Recognition of these lesions by ophthalmologists can help ensure appropriate etiologic evaluation and clinical investigation to define the range of anomalies in an affected infant and determine essential follow-up and ongoing care.
Keywords congenital Zika syndrome
ocular findings
Zika virus
xmlui.dri2xhtml.METS-1.0.item-coverage Philadelphia
Language English
Date 2017
Published in Current Opinion In Ophthalmology. Philadelphia, v. 28, n. 6, p. 595-599, 2017.
ISSN 1040-8738 (Sherpa/Romeo, impact factor)
Publisher Lippincott Williams & Wilkins
Extent 595-599
Origin http://dx.doi.org/10.1097/ICU.0000000000000420
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000418245600008
URI https://repositorio.unifesp.br/handle/11600/58216

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