Herpes zoster ophthalmicus and varicella zoster virus vasculopathy

Herpes zoster ophthalmicus and varicella zoster virus vasculopathy

Author Autor UNIFESP Google Scholar
Autor UNIFESP Google Scholar
Autor UNIFESP Google Scholar
Autor UNIFESP Google Scholar
Autor UNIFESP Google Scholar
Abstract Herpes zoster (HZ) corresponds to the reactivation of varicella zoster virus (VZV). Among adults, the ophthalmic division of the trigeminal nerve is one of the most common sites of involvement. Vasculopathy caused by HZ is associated with significant morbidity and mortality, affecting structures such as the brain, which can lead to stroke. In this review, we analyzed the epidemiological and clinical aspects of the vascular involvement of VZV, focusing on the peculiarities of its association with ocular HZ. A review of the available literature indicated that ocular involvement of HZ was a risk factor for vasculopathy after adjusting for age, sex, body mass index, smoking, indicators of metabolic syndrome, and vascular and heart diseases. Considering the severity of this complication, vascular disease mediated by VZV requires early diagnosis and aggressive treatment. Finally, the anti-HZ vaccine has been recommended as a prophylactic measure in the elderly, but it should be used with caution in immunocompromised individuals.
Keywords Herpesvirus 3
human
Herpes zoster ophthalmicus
Stroke
Herpes zoster vaccine
xmlui.dri2xhtml.METS-1.0.item-coverage Sao Paulo
Language English
Date 2016
Published in Arquivos Brasileiros De Oftalmologia. Sao Paulo, v. 79, n. 2, p. 126-129, 2016.
ISSN 0004-2749 (Sherpa/Romeo, impact factor)
Publisher Consel Brasil Oftalmologia
Extent 126-129
Origin http://dx.doi.org/10.5935/0004-2749.20160038
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000377714700018
SciELO ID S0004-27492016000200126 (statistics in SciELO)
URI https://repositorio.unifesp.br/handle/11600/57822

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