Sponsored multicentric clinical research conducted in Brazil in the respiratory area - losses and gains

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dc.contributor.author da Silveira Carvalho, Andrea Kelly
dc.contributor.author Nascimento, Oliver Augusto
dc.contributor.author Machado Fonseca, Marcelo Cunio [UNIFESP]
dc.contributor.author Barros Pereira, Eanes Delgado
dc.contributor.author Jardim, Jose Roberto [UNIFESP]
dc.date.accessioned 2020-08-21T16:59:58Z
dc.date.available 2020-08-21T16:59:58Z
dc.date.issued 2016
dc.identifier http://dx.doi.org/10.1590/1806-9282.62.02.131
dc.identifier.citation Revista Da Associacao Medica Brasileira. Sao Paulo, v. 62, n. 2, p. 131-137, 2016.
dc.identifier.issn 0104-4230
dc.identifier.uri https://repositorio.unifesp.br/handle/11600/57816
dc.description.abstract Objective: To evaluate the sponsored centers for clinical trial in the respiratory care setting in Brazil: profile; logistics and structure. Methods: Principal investigators (29) and subinvestigators (30) of 39 research centers completed the questionnaires that addressed personal identification and training of researchers, the centers' facilities and advantages and/or disadvantages of performing sponsored trials. Results: 75.6% of the centers were located in southern and southeastern Brazil. Most principal investigators were men with a mean age of 53.4 years. The clinical trials in the respiratory care setting focus on asthma and chronic obstructive pulmonary disease (COPD). 80% of the researchers cited delay of the Conep and Anvisa as a barrier to performing research. The advantages of participating in clinical trials were updating knowledge of the researcher and the team, and additional income for the team. The main disadvantages mentioned by the researchers included low financial compensation for the performed workload, and time availability. The median number of professionals per research center was six people, predominantly physicians. Conclusion: The number of research centers in the respiratory care setting in Brazil is still relatively small. The teams have good training for performing the clinical trials. Asthma and COPD are the most studied diseases in sponsored clinical trials. The main barrier is delay by the Conep and Anvisa. The factors that lead investigators to participate range from being updated along with the team, to site and staff financial issues; the main disadvantage is the low compensation for the required workload demand. en
dc.format.extent 131-137
dc.language.iso eng
dc.publisher Assoc Medica Brasileira
dc.relation.ispartof Revista Da Associacao Medica Brasileira
dc.rights Acesso aberto
dc.subject Biomedical research en
dc.subject drug industry en
dc.subject clinical trials as topic en
dc.title Sponsored multicentric clinical research conducted in Brazil in the respiratory area - losses and gains en
dc.type Artigo
dc.description.affiliation Univ Fortaleza Unifor, Grad Program Cardioresp Physiotherapy, Fortaleza, CE, Brazil
dc.description.affiliation Xlung Pulmoctr, Fortaleza, CE, Brazil
dc.description.affiliation Univ Fed Sao Paulo, Pulm Rehabil Ctr, Sao Paulo, SP, Brazil
dc.description.affiliation Univ Fed Sao Paulo, Dept Gynecol, Womens Hlth Area, Technol Assessment Serv, Sao Paulo, SP, Brazil
dc.description.affiliation Univ Fed Ceara, Dept Internal Med, Fortaleza, CE, Brazil
dc.description.affiliation Univ Fed Sao Paulo, Pneumol, Escola Paulista Med, Sao Paulo, SP, Brazil
dc.description.affiliationUnifesp Univ Fed Sao Paulo, Pulm Rehabil Ctr, Sao Paulo, SP, Brazil
dc.description.affiliationUnifesp Univ Fed Sao Paulo, Dept Gynecol, Womens Hlth Area, Technol Assessment Serv, Sao Paulo, SP, Brazi
dc.description.affiliationUnifesp Univ Fed Sao Paulo, Pneumol, Escola Paulista Med, Sao Paulo, SP, Brazil
dc.identifier.file S0104-42302016000200131-en.pdf
dc.identifier.scielo S0104-42302016000200131
dc.identifier.doi 10.1590/1806-9282.62.02.131
dc.description.source Web of Science
dc.identifier.wos WOS:000378266400006
dc.coverage Sao Paulo
dc.citation.volume 62
dc.citation.issue 2



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