High voltage pulsed current in collagen realignment, synthesis, and angiogenesis after Achilles tendon partial rupture

High voltage pulsed current in collagen realignment, synthesis, and angiogenesis after Achilles tendon partial rupture

Author Rampazo, Erika P. Autor UNIFESP Google Scholar
Liebano, Richard E. Google Scholar
Pinfildi, Carlos Eduardo Autor UNIFESP Google Scholar
Folha, Roberta A. C. Autor UNIFESP Google Scholar
Ferreira, Lydia M. Autor UNIFESP Google Scholar
Abstract Objective: To verify the efficacy of high voltage pulsed current in collagen realignment and synthesis and in angiogenesis after the partial rupturing of the Achilles tendon in rats. Method: Forty male Wistar rats were randomized into four groups of 10 animals each: sham, cathodic stimulation, anodic stimulation, and alternating stimulation. Their Achilles tendons were submitted to direct trauma by a free-falling metal bar. Then, the treatment was administered for six consecutive days after the injury. In the simulation group, the electrodes were positioned on the animal, but the device remained off for 30 minutes. The other groups used a frequency of 120 pps, sensory threshold, and the corresponding polarity. On the seventh day, the tendons were removed and sent for histological slide preparation for birefringence and Picrosirius Red analysis and for blood vessel quantification. Results: No significant difference was observed among the groups regarding collagen realignment (types I or III collagen) or quantity of blood vessels. Conclusion: High voltage pulsed current for six consecutive days was not effective in collagen realignment, synthesis, or angiogenesis after the partial rupturing of the Achilles tendon in rats.
Keywords electrical stimulation
tendinopathy
healing
physical agents
tissue repair
physical therapy
xmlui.dri2xhtml.METS-1.0.item-coverage Sao Carlos Sp
Language English
Date 2016
Published in Brazilian Journal Of Physical Therapy. Sao Carlos Sp, v. 20, n. 4, p. 312-319, 2016.
ISSN 1413-3555 (Sherpa/Romeo, impact factor)
Publisher Associacao Brasileira Pesquisa Pos-Graduacao Fisioterapia-Abrapg-Ft
Extent 312-319
Origin http://dx.doi.org/10.1590/bjpt-rbf.2014.0167
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000383791500004
SciELO ID S1413-35552016000400312 (statistics in SciELO)
URI https://repositorio.unifesp.br/handle/11600/57617

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