Inhaled nitric oxide and high concentrations of oxygen in pediatrics patients with congenital cardiopathy and pulmonary hypertension: report of five cases

Inhaled nitric oxide and high concentrations of oxygen in pediatrics patients with congenital cardiopathy and pulmonary hypertension: report of five cases

Author Carvalho, Werther Brunow de Autor UNIFESP Google Scholar
Carvalho, Antonio Carlos Autor UNIFESP Google Scholar
Gurgueira, Gisele Limongeli Autor UNIFESP Google Scholar
Ikeda, Angela Mityo Autor UNIFESP Google Scholar
Lee, June Ho Autor UNIFESP Google Scholar
Almeida, Dirceu Rodrigues de Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract Five patients with ages ranging from 6 months to 3 years were analyzed. All received inhaled nitric oxide (NO - 20 parts per million (ppm) ) and oxygen (0(2) - at a concentration of 90-95%) by means of an oxygen hood. Mean Pulmonary Artery Pressure (MPAP), Mean Aortic Pressure (MAoP), Pulmonary Vascular Resistance (PVR) and Systemic Vascular Resistance (SVR) were measured and the calculation of their relationship to pulmonary/systemic flow (Qp/Qs) was performed by the catheterization' of the femoral artery vein. Three patients presented reduction in PVR and increase in Qp/Qs. There were no systemic alterations or any side effect from using NO.

Cinco pacientes com cardiopatia congênita e hipertensão pulmonar receberam o oxido nítrico (NO - 20 partes por milhão (ppm)) inalatório e o oxigênio ( O2) na concentração de 90-95%) ) por meio de uma tenda de oxigênio. Através do cateterismo da artéria e veia femural foram mensuradas as pressão média de artéria pulmonar ( PmAP), pressão média de aorta (PmAo), resistência vascular pulmonar ( RVP), resistência vascular sistêmica (RVS) e feito o cálculo da relação fluxo pulmonar/sistêmico ( Qp/Qs). Três pacientes apresentaram uma redução na RVP e um aumento no Qp/Qs. Não foram observadas alterações sistêmicas ou qualquer efeito colateral com a utilização do NO.
Keywords Nitric Oxide
Pulmonary Hypertension
Congenital Cardiopathy
Language English
Date 1998-02-01
Published in São Paulo Medical Journal. Associação Paulista de Medicina - APM, v. 116, n. 1, p. 1602-1605, 1998.
ISSN 1516-3180 (Sherpa/Romeo)
Publisher Associação Paulista de Medicina - APM
Extent 1602-1605
Origin http://dx.doi.org/10.1590/S1516-31801998000100002
Access rights Open access Open Access
Type Article
SciELO ID S1516-31801998000100002 (statistics in SciELO)
URI http://repositorio.unifesp.br/handle/11600/574

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