Chronic hepatitis B and D: prognosis according to Child-Pugh score

Chronic hepatitis B and D: prognosis according to Child-Pugh score

Alternative title Hepatites crônicas B e D: prognóstico segundo escore Child-Pugh
Author de Oliveira, Marcelo Siqueira Autor UNIFESP Google Scholar
Martins Silva, Romeu Paulo Google Scholar
Negreiros do Valle, Suiane da Costa Google Scholar
de Figueiredo, Elisabeth Niglio Autor UNIFESP Google Scholar
Fram, Dayana Autor UNIFESP Google Scholar
Abstract Objective: compare chronic hepatitis B patients to those superinfected with hepatitis D virus, according to Child-Pugh score regarding disease severity. Method: retrospective descriptive study, performed with 59 patients followed in the ambulatory, of which 22 (37.3%) were chronically infected with hepatitis B virus (Group HBV) and 37 (62.7%) superinfected with Delta virus (Group HBV+HDV)

variables of sex, age and items of Child-Pugh score were collected by consulting medical records. Results: out of the patients, 57.6% were male, with a mean age of 30.5 years. Score A, which indicates lesser severity, was found in 100% of group HBV and 78.4% of group HBV+HDV. Score B, which indicates greater severity, was found only in group HBV+HDV in 21.6% of the patients. Conclusion: by means of the Child-Pugh score, it was observed that patients with superinfection by HDV tended to present a worse prognosis.

Objetivo: comparar os pacientes com hepatite B crônica com superinfectados pelo vírus D segundo escore de Child-Pugh quanto à gravidade da doença. Método: estudo descritivo retrospectivo, realizado com 59 pacientes acompanhados em ambulatório, sendo 22 (37,3%) cronicamente infectados pelo vírus da hepatite B (Grupo VHB) e 37 (62,7%) com superinfecção por vírus Delta (Grupo VHB+VHD); foram coletadas variáveis quanto ao sexo, idade e referentes ao escore de Child-Pugh por meio de consulta a prontuários. Resultados: entre os pacientes 57,6% era do sexo masculino, com idade média de 30,5 anos. O escore A, que indica menor gravidade, foi encontrado em 100% do grupo VHB e 78,4% do grupo VHB+VHD. O escore B, que indica maior gravidade, foi encontrado apenas no grupo VHB+VHD em 21,6% dos pacientes. Conclusão: por meio do escore de Child-Pugh, observou-se que os pacientes com superinfecção por VHD tendem a apresentar pior prognóstico.
Keywords Hepatitis B
Hepatitis D
Prognosis
Gastroenterology
Infectology
Hepatite B
Hepatite D
Prognóstico
Gastroenterologia
Infectologia
xmlui.dri2xhtml.METS-1.0.item-coverage Brasilia Df
Language English
Portuguese
Date 2017
Published in Revista Brasileira De Enfermagem. Brasilia Df, v. 70, n. 5, p. 1048-1053, 2017.
ISSN 0034-7167 (Sherpa/Romeo, impact factor)
Publisher Assoc Brasileira Enfermagem
Extent 1048-1053
Origin http://dx.doi.org/10.1590/0034-7167-2016-0205
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000416651400022
SciELO ID S0034-71672017000501048 (statistics in SciELO)
URI https://repositorio.unifesp.br/handle/11600/57392

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