Brazilian-Portuguese translation, cross-cultural adaptation and validation of the Myasthenia Gravis Composite scale. A multicentric study

Brazilian-Portuguese translation, cross-cultural adaptation and validation of the Myasthenia Gravis Composite scale. A multicentric study

Author Oliveira, Ezequiel Fernandes Google Scholar
Lima, Valeria Cavalcante Autor UNIFESP Google Scholar
Perez, Eduardo Araujo Google Scholar
Polaro, Melissa Nunes Google Scholar
Oliveira Valerio, Berenice Cataldo Google Scholar
Pereiro, Joao R. Google Scholar
Nacif, Sergio Roberto Google Scholar
Oliveira, Claudia Santos Google Scholar
Oliveira, Acary Souza Bulle Autor UNIFESP Google Scholar
Franco Oliveira, Luis Vicente Google Scholar
Abstract Objective: To perform the translation, cultural adaptation and validation of the Myasthenia Gravis Composite (MGC) scale in Brazil. Methods: The study was conducted at three neuromuscular disease research centers in accordance with the international ethical standards, following a multi-modal approach and was conducted in three steps consisting of translation, cultural adaptation, and validation according to international guidelines. The final version of the MGC was applied in a sample of 27 MG patients and the total score was compared to a Portuguese version of the MG-QOL-15. Results: The internal consistency verified by Cohen's Kappa test was excellent (0.766). The correlation between the MGC and MG-QOL-15 was strong (R = 0.777

p = 0.000). No significant differences were found between the responses of patients in the first and second applications of the MGC. Conclusion: The MGC scale, validated into Brazilian Portuguese, has proven to be a reliable instrument that is easy to use, and is highly reproducible.
Keywords myasthenia gravis
translating
surveys and questionaires
xmlui.dri2xhtml.METS-1.0.item-coverage Sao Paulo Sp
Language English
Sponsor Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Grant number CNPq: 313053/2014-6
FAPESP: 2015/11738-6
Date 2016
Published in Arquivos De Neuro-Psiquiatria. Sao Paulo Sp, v. 74, n. 11, p. 914-920, 2016.
ISSN 0004-282X (Sherpa/Romeo, impact factor)
Publisher Assoc Arquivos Neuro- Psiquiatria
Extent 914-920
Origin http://dx.doi.org/10.1590/0004-282X20160129
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000388579300011
SciELO ID S0004-282X2016001100914 (statistics in SciELO)
URI https://repositorio.unifesp.br/handle/11600/56819

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