Reliable assessment of forearm photoageing by high-frequency ultrasound: a cross-sectional study

Reliable assessment of forearm photoageing by high-frequency ultrasound: a cross-sectional study

Author Caetano, L. de V. N. Autor UNIFESP Google Scholar
Soares, J. L. M. Autor UNIFESP Google Scholar
Bagatin, Edileia Autor UNIFESP Google Scholar
Miot, H. A. Google Scholar
Abstract OBJECTIVE: High-frequency ultrasound is a non-invasive tool used in skin ageing research to assess dermis thickness and echogenicity. This study evaluated the reliability of a range of high-frequency ultrasound parameters and tested their correlation with age and a validated clinical scale for the assessment of forearm skin photoageing

the difference between two body sites according to environmental exposition patterns was also investigated. METHODS: Twenty-three volunteers aged 28-82 years were divided into three groups according to forearm photoageing degree. A 20 MHz ultrasound unit was used to obtain cross-sectional images of the skin by two trained investigators on two different sites: the dorsal forearm (chronically photoexposed skin) and the proximal medial arm (non-photoexposed skin). Several echogenicity parameters were studied for each skin compartment: total dermis, upper dermis and lower dermis, and the ratio between upper and lower dermis. RESULTS: The intraclass correlation coefficient (for complete agreement) between investigators was higher for upper and total dermis echogenicity measures compared with the lower dermis. At the non-photoexposed site, the upper and lower dermis parameter ratio was better correlated with age. At the photoexposed area, total dermis parameters demonstrated higher correlations with clinical score. CONCLUSION: The authors discuss the choice of parameters for forearm photoageing assessment using high-frequency ultrasound.
Keywords safety testing
skin ageing
skin physiology/structure
statistics
ultrasonography
xmlui.dri2xhtml.METS-1.0.item-coverage Hoboken
Language English
Sponsor FUNADERSP, an organization of the Sao Paulo regional office of the Brazilian Society of Dermatology (SBD-RESP)
Grant number SBD-RESP: 001/2013
Date 2016
Published in International Journal Of Cosmetic Science. Hoboken, v. 38, n. 2, p. 170-177, 2016.
ISSN 0142-5463 (Sherpa/Romeo, impact factor)
Publisher Wiley-Blackwell
Extent 170-177
Origin http://dx.doi.org/10.1111/ics.12272
Access rights Closed access
Type Article
Web of Science ID WOS:000372661200008
URI https://repositorio.unifesp.br/handle/11600/56168

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