Severe liver and renal injuries following cerebral angiography: late life-threatening complications of non-ionic contrast medium administration

Severe liver and renal injuries following cerebral angiography: late life-threatening complications of non-ionic contrast medium administration

Author Silva, Paulo Sergio Lucas da Autor UNIFESP Google Scholar
Kubo, Emerson Yukio Autor UNIFESP Google Scholar
Fonseca, Marcelo Cunio Machado Autor UNIFESP Google Scholar
Abstract Contrast-induced nephropathy requiring dialysis support is rarely reported, whereas severe liver injury after contrast agent administration has not been described in children yet. A previously healthy 10-year-old boy with diagnosis of cerebral arteriovenous malformation underwent a cerebral angiogram study with iohexol (3 mL/kg). After 4 days, he developed vomiting and abdominal pain. Laboratory results showed abnormal liver function tests, including marked elevation of transaminases. In the next day, he evolved with oliguria and blood arterial hypertension. At this time, he presented with worsening renal function tests. Peritoneal dialysis was required for 13 days. The patient had a self-limiting course and received only supportive treatment. This report highlights delayed complications related to low non-ionic contrast media with a rare presentation that can be neglected or unrecognized by pediatric specialties.
Keywords Children
Contrast media
Liver
Renal failure
xmlui.dri2xhtml.METS-1.0.item-coverage New York
Language English
Date 2016
Published in Childs Nervous System. New York, v. 32, n. 4, p. 733-737, 2016.
ISSN 0256-7040 (Sherpa/Romeo, impact factor)
Publisher Springer
Extent 733-737
Origin http://dx.doi.org/10.1007/s00381-015-2889-x
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000373299100024
URI https://repositorio.unifesp.br/handle/11600/56148

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