High Blood Pressure during Pregnancy is not a Protective Factor for Preterm Infants with Very Low Birth Weight. A Case-Control Study

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dc.contributor.author Sabino, Annibal Tagliaferri [UNIFESP]
dc.contributor.author de Souza, Eduardo [UNIFESP]
dc.contributor.author Goulart, Ana Lucia [UNIFESP]
dc.contributor.author de Lima, Adriana Martins [UNIFESP]
dc.contributor.author Sass, Nelson [UNIFESP]
dc.date.accessioned 2020-07-17T14:02:19Z
dc.date.available 2020-07-17T14:02:19Z
dc.date.issued 2017
dc.identifier http://dx.doi.org/10.1055/s-0037-1601883
dc.identifier.citation Revista Brasileira De Ginecologia E Obstetricia. Rio De Janeiro Rj, v. 39, n. 4, p. 155-161, 2017.
dc.identifier.issn 0100-7203
dc.identifier.uri https://repositorio.unifesp.br/handle/11600/54736
dc.description.abstract Objective To evaluate whether the presence of maternal blood pressure reduces the risks of morbidity, perinatal mortality and morbidity at 24 months of age in very low birth weight infants (VLBWIs) compared with a control group. Methods A retrospective, observational, case-control study. Total 49 VLBWIs were allocated to the study group, called the maternal arterial hypertension group (AHG), and matched with 44 in the control group (CG). The infants were assessed during hospitalization and at 12 and 24 months corrected age at a specialized clinic. For the assessment of growth, the World Health Organization (WHO) Anthro software (Geneva, 2006) was used, and for the psychomotor assessment, the Denver II test was used. Results In relation to the antenatal variables, the infants of the AHG had more centralized circulation assessed by Doppler, received more corticosteroids and magnesium sulfate, and were born by cesarean section more frequently. In terms of the postnatal and in-hospital outcomes, the AHG had a higher gestational age at birth (30.7 versus 29.6 weeks) and a lower frequency of 5-minute Apgar scores of less than 7 (26.5% versus 52.3%). The CG had a higher rate of pulmonary dysplasia (30.2% versus 8.3%). There were no differences in terms of hospital mortality, complications, somatic growth and functional problems at 24 months of corrected age. Conclusion The presence ofmaternal hypertension, especially preeclampsia, was not a protective factor against morbidity, mortality and evolution in VLBWIs aged up to 24 months. Therefore, the clinical practice should be focused on prolonging the pregnancy for as long as possible in these conditions as well. en
dc.description.sponsorship Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP)
dc.format.extent 155-161
dc.language.iso eng
dc.publisher Federacao Brasileira Soc Ginecologia & Obstetricia-Febrasgo
dc.relation.ispartof Revista Brasileira De Ginecologia E Obstetricia
dc.rights Acesso aberto
dc.subject premature birth en
dc.subject child development en
dc.subject preeclampsia en
dc.title High Blood Pressure during Pregnancy is not a Protective Factor for Preterm Infants with Very Low Birth Weight. A Case-Control Study en
dc.type Artigo
dc.description.affiliation Univ Fed Sao Paulo, Dept Obstet, Escola Paulista Med, Sao Paulo, SP, Brazil
dc.description.affiliation Univ Fed Sao Paulo, Dept Pediat, Escola Paulista Med, Sao Paulo, Brazil
dc.description.affiliationUnifesp Univ Fed Sao Paulo, Dept Obstet, Escola Paulista Med, Sao Paulo, SP, Brazil
dc.description.affiliationUnifesp Univ Fed Sao Paulo, Dept Pediat, Escola Paulista Med, Sao Paulo, Brazil
dc.description.sponsorshipID FAPESP: 2014/00213-7
dc.identifier.file WOS000410251900003.pdf
dc.identifier.doi 10.1055/s-0037-1601883
dc.description.source Web of Science
dc.identifier.wos WOS:000410251900003
dc.coverage Rio De Janeiro Rj
dc.citation.volume 39
dc.citation.issue 4



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