Multiple sclerosis risk perception and acceptance for Brazilian patients

Multiple sclerosis risk perception and acceptance for Brazilian patients

Author Bichuetti, Denis Bernardi Google Scholar
Franco, Carolina Azze Google Scholar
Elias, Isaac Google Scholar
Mendonca, Andreia C. R. Google Scholar
Diniz Carvalho, Lorraine Fiama Google Scholar
Diniz, Denise Sisterolli Google Scholar
Tur, Carmen Google Scholar
Tintore, Mar Google Scholar
Lobato de Oliveira, Enedina Maria Google Scholar
Abstract The perception of multiple sclerosis (MS) severity and risk associated with therapies might influence shared decision making in different countries. We investigated the perception of MS severity and factors associated with risk acceptance in Brazil in 96 patients with relapsing-remitting MS using a standardized questionnaire and compared this with two European cohorts. Multiple sclerosis was perceived as a very severe disease and the risk of developing progressive multifocal leukoencephalopathy due to natalizumab was seen as moderate to high. Seventy-six percent considered a risk of 1:1,000, or higher, an impediment for natalizumab use. Older age was the only variable associated with higher risk acceptance and our patients showed a more conservative profile than German and Spanish patients. Our patients perceived MS severity and progressive multifocal leukoencephalopathy risk similarly to elsewhere, but their willingness to take risks was more conservative. This should be considered when discussing therapeutic options and it might have an impact on guideline adaptations.
Keywords multiple sclerosis
risk assessment
decision making
xmlui.dri2xhtml.METS-1.0.item-coverage Sao Paulo Sp
Language English
Date 2018
Published in Arquivos De Neuro-Psiquiatria. Sao Paulo Sp, v. 76, n. 1, p. 6-12, 2018.
ISSN 0004-282X (Sherpa/Romeo, impact factor)
Publisher Assoc Arquivos Neuro- Psiquiatria
Extent 6-12
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000422938800003

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