Current Practices in Ocular Toxoplasmosis: A Survey of Brazilian Uveitis Specialists

Current Practices in Ocular Toxoplasmosis: A Survey of Brazilian Uveitis Specialists

Author Morais, Fabio Barreto Autor UNIFESP Google Scholar
Faria e Arantes, Tiago Eugenio Google Scholar
Muccioli, Cristina Autor UNIFESP Google Scholar
Abstract Purpose: To describe treatment practices for ocular toxoplasmosis among members of the Brazilian Uveitis Society.Methods: An online questionnaire sent to specialists, between October 2014 and March 2015.Results: Most respondents (67.9%) treat all active cases. Most specialists consider visual acuity <20/200 (88.2%), severe vitreous inflammation (94.1%), and ocular disease during acquired infection (88.2%) as absolute indications for treatment. Systemic steroids are associated with anti-toxoplasmic therapy in most cases by 50.9% of the respondents. For immunocompetent individuals, 57.4% of the respondents chose trimethoprim/sulfamethoxazole. Classical therapy (sulfadiazine/pyrimethamine) is preferred most for patients with central lesions (70.4%), immunosuppression (68.4%), acquired infection (70.4%), and atypical forms (74.1%). For patients with frequent relapses, 84.9% of the respondents preferred antibiotic prophylaxis.Conclusions: Treatment patterns of ocular toxoplasmosis are not uniform among Brazilian specialists. Most specialists treat all cases of active retinochoroiditis. Typical cases are more frequently treated with trimethoprim/sulfamethoxazole. However, classical therapy is the regimen of choice when lesions are considered more severe.
Keywords Antibiotics
ocular toxoplasmosis
xmlui.dri2xhtml.METS-1.0.item-coverage Philadelphia
Language English
Date 2018
Published in Ocular Immunology And Inflammation. Philadelphia, v. 26, n. 2, p. 317-323, 2018.
ISSN 0927-3948 (Sherpa/Romeo, impact factor)
Publisher Taylor & Francis Inc
Extent 317-323
Access rights Closed access
Type Article
Web of Science ID WOS:000426938900029

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