Phonetic and phonological aspects of speech in Alzheimer's disease

Phonetic and phonological aspects of speech in Alzheimer's disease

Author Cera, Maysa Luchesi Google Scholar
Ortiz, Karin Zazo Google Scholar
Ferreira Bertolucci, Paulo Henrique Google Scholar
Minett, Thais Google Scholar
Abstract Background: Alzheimer's disease (AD) can involve changes in communication and can lead to mutism in severe cases. Oral communication may be impaired by phonetic-motor disorders, such as apraxia of speech (AOS), or by language disorders, such as aphasia. Therefore, the identification of manifestations of AOS and phonemic paraphasias in patients with AD is critical to understanding the communication changes and determining the therapeutic planning. Aims: To identify the distribution of phonetic-phonological manifestations in older patients with AD and healthy older subjects and assess whether these manifestations indicate the origin of the changes, including a predominantly phonetic-motor origin, a predominantly phonological-linguistic origin, or both. Methods & Procedures: This cross-sectional study evaluated 90 patients with AD and 30 healthy older volunteers. All of the participants underwent the same repetition task for phonetic and phonological assessments using the current classification of phonetic-phonological manifestations

this classification distinguishes characteristics that are mostly related to AOS from other signs that are mostly related to aphasia. Negative binomial regression analysis was conducted to compare the amount of each manifestation presented by the two groups. Outcomes & Results: The patients with AD showed significantly more signs of aphasia (self-correction, and vowel and consonant substitutions), AOS (prolonged intervals and extended vowel duration), and AOS or aphasia (distortion, omission, attempts at the syllable level, distorted substitutions, and additions) than the healthy older volunteers. Conclusions: Older adults with AD presented phonetic and phonological changes of aphasia and AOS and, consequently, limitations in symbolic-linguistic planning and motor planning.
Keywords Speech-language pathology
Alzheimer's disease
xmlui.dri2xhtml.METS-1.0.item-coverage Abingdon
Language English
Sponsor State of Sao Paulo Research Foundation (FAPESP) [2008/52670-1]
National Council for Scientific and Technological Development (CNPq) [132979/2008-0]
Coordination for the Improvement of Higher Education Personnel (CAPES)
Academic Clinical Fellow from the National Institute for Health Research
Grant number FAPESP [2008/52670-1]
CNPq [132979/2008-0]
Date 2018
Published in Aphasiology. Abingdon, v. 32, n. 1, p. 88-102, 2018.
ISSN 0268-7038 (Sherpa/Romeo, impact factor)
Publisher Routledge Journals, Taylor & Francis Ltd
Extent 88-102
Access rights Closed access
Type Article
Web of Science ID WOS:000427198800006

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