Persistence of granular corneal dystrophy type-1 deposits in the predescemetic layer after big-bubble deep anterior lamellar keratoplasty

Persistence of granular corneal dystrophy type-1 deposits in the predescemetic layer after big-bubble deep anterior lamellar keratoplasty

Author Muller, Eduardo Gayger Autor UNIFESP Google Scholar
Pereira Gomes, Jose Alvaro Autor UNIFESP Google Scholar
Nose, Walton Autor UNIFESP Google Scholar
Nose, Ricardo Menon Autor UNIFESP Google Scholar
Abstract We report intraoperative finding of Granular Corneal Dystrophy Type-1 (GCD1) deposits after stromal pneumodissection in deep anterior lamellar keratoplasty (DALK) in a 61-year-old female. Pneumodissection was performed from the center to the periphery of the cornea, characterizing a big bubble type 1 technique which dissects the deep stroma from the predescemetic layer. After stromal removal, persistence of whitish deposits inside the predescemetic layer was noted. During post-operative evaluation, anterior biomicroscopy and anterior segment optical coherence tomography showed granular opacities between the patient's Descemet's membrane and the donor cornea, suggesting possible involvement of the predescemetic layer in GCD1. This may require the surgeon's attention to choose between DALK keratoplasty or penetrating keratoplasty.
Keywords Corneal dystrophies, hereditary
Corneal transplantation
Cornea
Corneal diseases
Descemet membranes
xmlui.dri2xhtml.METS-1.0.item-coverage Sao Paulo
Language English
Date 2018
Published in Arquivos Brasileiros De Oftalmologia. Sao Paulo, v. 81, n. 1, p. 66-69, 2018.
ISSN 0004-2749 (Sherpa/Romeo, impact factor)
Publisher Consel Brasil Oftalmologia
Extent 66-69
Origin http://dx.doi.org/10.5935/0004-2749.20180015
Access rights Closed access
Type Article
Web of Science ID WOS:000427401000015
URI https://repositorio.unifesp.br/handle/11600/53833

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