Trichotillomania: a good response to treatment with N-acetylcysteine

Trichotillomania: a good response to treatment with N-acetylcysteine

Author Lopes Barroso, Livia Ariane Autor UNIFESP Google Scholar
Sternberg, Flavia Autor UNIFESP Google Scholar
Inacio de Fraia e Souza, Maria Natalia Autor UNIFESP Google Scholar
de Barros Nunes, Gisele Jacobino Autor UNIFESP Google Scholar
Abstract Trichotillomania is considered a behavioral disorder and is characterized by the recurring habit of pulling one's hair, resulting in secondary alopecia. It affects 1% of the adult population, and 2 to 4.4% of psychiatric patients meet the diagnostic criteria. It can occur at any age and is more prevalent in adolescents and females. Its occurrence in childhood is not uncommon and tends to have a more favorable clinical course. The scalp, eyebrows and eyelashes are the most commonly affected sites. Glutamate modulating agents, such as N-acetylcysteine, have been shown to be a promising treatment. N-acetylcysteine acts by reducing oxidative stress and normalizing glutaminergic transmission. In this paper, we report a case of trichotillomania with an excellent response to N-acetylcysteine.
Keywords Acetylcysteine
Alopecia
Glutamates
Trichotillomania
xmlui.dri2xhtml.METS-1.0.item-coverage Rio De Janeiro Rj
Language English
Date 2017
Published in Anais Brasileiros De Dermatologia. Rio De Janeiro Rj, v. 92, n. 4, p. 537-539, 2017.
ISSN 0365-0596 (Sherpa/Romeo, impact factor)
Publisher Soc Brasileira Dermatologia
Extent 537-539
Origin http://dx.doi.org/10.1590/abd1806-4841.20175435
Access rights ACESSO ABERTO
Type Article
Web of Science ID WOS:000411799300016
SciELO ID S0365-05962017000400537 (statistics in SciELO)
URI https://repositorio.unifesp.br/handle/11600/53516

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