Juvenile systemic lupus erythematosus: neurological involvement

Juvenile systemic lupus erythematosus: neurological involvement

Alternative title Lupus erítematoso sistêmico juvenil: comprometimento neurológico
Author Schmutzler, Katia M.r.s. Google Scholar
Vilanova, Luiz Celso Pereira Autor UNIFESP Google Scholar
Lima, José Geraldo C. Autor UNIFESP Google Scholar
Hilário, Maria Odete Esteves Autor UNIFESP Google Scholar
Naspitz, Charles Kirov Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract With the purpose of analyzing the neurological involvement due to systemic lupus erythematosus (SLE), we evaluated 17 female patients who were seen regularly at the hospital and had been diagnosed as having SLE according to classification criteria proposed by the American College of Rheumatology revised in 1982, before the age of 16. Neurological involvement was detected in 12 patients (71%): headache (35%), extrapyramidal syndrome (35%), epileptic syndrome (24%) pyramidal syndrome (24%), peripheral neuropathy (12%) and optic neuritis (6%). The findings of CT scan (58%) and cerebrospinal fluid (50%) were most closely correlated to clinical neurological involvement.

Com o objetivo de analisar o comprometimento neurológico secundário ao lupus eritematoso sistêmico (LES), avaliamos pacientes que estavam em acompanhamento ambulatorial. Foram selecionadas 17 pacientes do sexo feminino cujo diagnóstico do LES foi até a idade de 16 anos, e preencheu os critérios para a classificação propostos pelo Colégio Americano de Reumatologia revisados em 1982. O comprometimento neurológico foi observado em 12 pacientes (71%): cefaléia (35%), síndrome extrapiramidal (35%), síndrome epiléptica (24%), síndrome piramidal (24%), neuropatia periférica (12%) e neurite óptica (6%). Dos exames complementares a tomografia coputadorizada de crânio (58%) e o líquido cefalorraquidiano (50%) mostraram maior correlação com a presença de comprometimento neurológico.
Keywords juvenile systemic lupus erythematosus
neurological involvement
lupus eritematoso sistêmico juvenil
comprometimento neurológico
Language English
Date 1997-09-01
Published in Arquivos de Neuro-Psiquiatria. Academia Brasileira de Neurologia - ABNEURO, v. 55, n. 3B, p. 606-609, 1997.
ISSN 0004-282X (Sherpa/Romeo, impact factor)
Publisher Academia Brasileira de Neurologia - ABNEURO
Extent 606-609
Origin http://dx.doi.org/10.1590/S0004-282X1997000400016
Access rights Open access Open Access
Type Article
Web of Science ID WOS:A1997XZ27300016
SciELO ID S0004-282X1997000400016 (statistics in SciELO)
URI http://repositorio.unifesp.br/handle/11600/527

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