The visual system in infants with microcephaly related to presumed congenital Zika syndrome

The visual system in infants with microcephaly related to presumed congenital Zika syndrome

Author Vercosa, Islane Google Scholar
Carneiro, Paula Google Scholar
Vercosa, Reno Google Scholar
Girao, Renata Google Scholar
Ribeiro, Erlane M. Google Scholar
Pessoa, Andre Google Scholar
Almeida, Nadia G. Google Scholar
Vercosa, Paloma Google Scholar
Tartarella, Marcia B. Autor UNIFESP Google Scholar
Abstract PURPOSE To describe and analyze ocular features in infants with microcephaly due to presumed congenital Zika syndrome. METHODS Ophthalmologic evaluation, including indirect ophthalmoscopy and eye fundus imaging, visual acuity testing with Teller Acuity Cards, and strabismus assessment were performed in infants with microcephaly at a nongovernmental organization clinic for visually disabled children. RESULTS A total of 70 infants with microcephaly were referred to the clinic. Of these, 25 (mean age, 3 months

14 males) had ophthalmologic changes: 18 (26%) had intraocular abnormalities, including macular chorioretinal atrophy, mottled retinal pigment epithelium and optic nerve pallor

7 patients (10%) had strabismus or nystagmus without intraocular abnormalities. Visual acuity was below normal range in all 11 infants tested. CONCLUSIONS Ophthalmologic abnormalities occurred in 36% of the patients. Macular circumscribed chorioretinal atrophy, focal mottled retinal pigment epithelium, optic nerve pallor, early-onset strabismus, nystagmus and low visual acuity were common ophthalmological features in infants with microcephaly due to presumed congenital Zika syndrome. (J AAPOS 2017;21:300-304)
Language English
Date 2017
Published in Journal Of Aapos. New York, v. 21, n. 4, p. 300-304, 2017.
ISSN 1091-8531 (Sherpa/Romeo, impact factor)
Publisher Mosby-Elsevier
Extent 300-304
Origin http://dx.doi.org/10.1016/j.jaapos.2017.05.024
Access rights Closed access
Type Article
Web of Science ID WOS:000409565500011
URI http://repositorio.unifesp.br/handle/11600/51427

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