Genotoxicity Induced by Dental Materials: A Comprehensive Review

Genotoxicity Induced by Dental Materials: A Comprehensive Review

Author Ribeiro, Daniel Araki Autor UNIFESP Google Scholar
Yujra, Veronica Quispe Autor UNIFESP Google Scholar
Gomes De Moura, Carolina Foot Autor UNIFESP Google Scholar
Handan, Bianca Andrade Autor UNIFESP Google Scholar
Viana, Milena De Barros Autor UNIFESP Google Scholar
Yamauchi, Liria Yuri Autor UNIFESP Google Scholar
Castelo, Paula Midori Autor UNIFESP Google Scholar
Aguiar, Odair, Jr. Autor UNIFESP Google Scholar
Abstract Genotoxicity is the capacity of an agent to produce damage in the DNA molecule. Considering the strong evidence for a relationship between genetic damage and carcinogenesis, evaluation of genotoxicity induced by dental materials is necessary for elucidating the true health risks to patients and professionals. The purpose of this article was to provide a comprehensive review of genotoxicity induced by dental materials. All published data showed some evidence of genotoxicity, especially related to dental bleaching, restorative materials and endodontic compounds. Certainly, such information will be added to that already established for regulatory purposes as a safe way to promote oral healthcare and prevent oral carcinogenesis.
Keywords Genotoxicity
dental materials
DNA damage
review
Language English
Date 2017
Published in Anticancer Research. Athens, v. 37, n. 8, p. 4017-4024, 2017.
ISSN 0250-7005 (Sherpa/Romeo, impact factor)
Publisher Int Inst Anticancer Research
Extent 4017-4024
Origin http://dx.doi.org/10.21873/anticanres.11786
Access rights Closed access
Type Revisão
Web of Science ID WOS:000412579000004
URI http://repositorio.unifesp.br/handle/11600/51406

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