The intensive care medicine research agenda on septic shock

The intensive care medicine research agenda on septic shock

Author Perner, Anders Google Scholar
Gordon, Anthony C. Google Scholar
Angus, Derek C. Google Scholar
Lamontagne, Francois Google Scholar
Machado, Flavia Autor UNIFESP Google Scholar
Russell, James A. Google Scholar
Timsit, Jean-Francois Google Scholar
Marshall, John C. Google Scholar
Myburgh, John Google Scholar
Shankar-Hari, Manu Google Scholar
Singer, Mervyn Google Scholar
Abstract Septic shock remains a global health challenge with millions of cases every year, high rates of mortality and morbidity, impaired quality of life among survivors and relatives, and high resource use both in developed and developing nations. Care and outcomes are improving through organisational initiatives and updated clinical practice guidelines based on clinical research mainly carried out by large collaborative networks. This progress is likely to continue through the collaborative work of the established and merging trials groups in many parts of the world and through refined trial methodology and translational work. In this review, international experts summarize the current position of clinical research in septic shock and propose a research agenda to advance this field.
Keywords Clinical research
Critical care
Intensive care
ICU
Randomized trials
Sepsis
Septic shock
Language English
Sponsor Ferring Pharmaceuticals
Fresenius Kabi
CSL Behring
Orion Pharmaceuticals
Amomed
Tenax Therapeutics
HCA International
NIHR
NIHR Research Professorship award
Abbott
Bayer
Beckman-Coulter
Biocartis
GenMark
GlaxoSmithKline
Sobi
Ferring
Baxter Healthcare
Practitioner Fellowship from the National Health and Medical Research Council of Australia
Grifols
La Jolla Pharmaceuticals
CytoVale Inc.
Asahi Kesai Pharmaceuticals of America (AKPA)
National Institute for Health Research Clinician Scientist Award
UK Department of Health
Grant number National Institute for Health Research Clinician Scientist Award: CS-2016-16-011
Date 2017
Published in Intensive Care Medicine. New York, v. 43, n. 9, p. 1294-1305, 2017.
ISSN 0342-4642 (Sherpa/Romeo, impact factor)
Publisher Springer
Extent 1294-1305
Origin http://dx.doi.org/10.1007/s00134-017-4821-1
Access rights Closed access
Type Article
Web of Science ID WOS:000408116700010
URI http://repositorio.unifesp.br/handle/11600/51344

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