Cancer treatment in determination of hearing loss

Cancer treatment in determination of hearing loss

Title: Cancer treatment in determination of hearing loss;
Tratamento oncológico na determinação das alterações auditivas
Author de Oliveira, Priscila Feliciano Google Scholar
Oliveira, Camila Silva Google Scholar
Andrade, Joice Santos Google Scholar
do Carmo Santos, Tamara Figueiredo Google Scholar
de Oliveira-Barreto, Aline Cabral Autor UNIFESP Google Scholar
Abstract Introduction: Chemotherapy and radiotherapy in oncology have repercussions in hearing health, and can damage structures of the inner ear. These repercussions usually, result in a bilateral and irreversible hearing loss. Objective: To identify sensorineural hearing toss cases with complaints of tinnitus and difficulty in speech understanding and investigate their relationship with the types of chemotherapy and radiotherapy the patients received. Methods: Cross-sectional, clinical, observational, analytical, historical cohort study of 58 subjects treated in a public hospital in the state of Sergipe, diagnosed with neoplasia. The subjects were submitted to anamnesis, conventional pure tone audiometry, and speech recognition threshold. Results: Of the 116 ears, 25.9% presented sensorioneural hearing loss characterized by changes in high frequencies. There was a positive correlation between hearing loss and the association of chemotherapy and radiotherapy (p= 0.035

R=0.196). The auditory complaint analysis shows that most of the subjects had tinnitus and speech understanding difficulty, even with a normal auditory threshold. Conclusions: Cancer treatment causes hearing loss, associated with the administration of chemotherapy and radiotherapy. Cyclophosphamide increased the risk of causing hearing loss. Complaints of tinnitus and speech understanding difficulty were observed. (C) 2015 Associacao Brasileira de Otorrinolaringologia e Cirurgia Cervico-Facial. Published by Elsevier Editora Ltda. All rights reserved.
Keywords Cancer
Hearing Loss
Chemotherapy
RadiotherapyRadiotherapy
Cisplatin
Head
Language English
Date 2016
Published in Brazilian Journal Of Otorhinolaryngology. Sao paulo, v. 82, n. 1, p. 65-69, 2016.
ISSN 1808-8694 (Sherpa/Romeo, impact factor)
Publisher Assoc brasileira otorrinolaringologia & cirurgia cervicofacial
Extent 65-69
Origin http://dx.doi.org/10.1016/j.bjorl.2014.12.010
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000371652200010
SciELO ID S1808-86942016000100065 (statistics in SciELO)
URI http://repositorio.unifesp.br/handle/11600/49586

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