Maternal risks and predictor factors for the termination of pregnancy in fetuses with severe congenital anomaly: experience from a single reference center in brazil

Maternal risks and predictor factors for the termination of pregnancy in fetuses with severe congenital anomaly: experience from a single reference center in brazil

Author Westphal, Flavia Autor UNIFESP Google Scholar
Araujo Junior, Edward Autor UNIFESP Google Scholar
Fustinoni, Suzete Maria Autor UNIFESP Google Scholar
Abrahao, Anelise Riedel Autor UNIFESP Google Scholar
Abstract Objective: To assess the maternal complications in pregnant women with fetuses with several congenital anomaly as well as the predictor variables for the termination of pregnancy.Methods: We performed a retrospective cohort study with 94 medical records of pregnant women with fetal infeasibility confirmed in the postnatal period by clinical, radiological or anatomopathological exams. To compare the categorical variables regarding the termination and nontermination of pregnancy, we used analysis of variance (ANOVA) and the Mann-Whitney U-test. To assess the variables that were more associated with the judicial request for the termination of pregnancy, we used logistic regression.Results: The termination of pregnancy was performed in 41 (43.6%) and nontermination of pregnancy in 53 (56.4%) pregnant women. Pregnant women who did not terminate the pregnancy had more complications in the gestational period (p<0.0001) and in the postpartum period (p = 0.0088). After multiple logistic regressions, the following variables influenced the decision to terminate the pregnancy: type of congenital anomaly (OR: 18.59

95%CI: 1.96

175.87) and living children (OR: 0.45

95%CI: 0.25

0.80).Conclusion: Most of the pregnant women with fetal infeasibility opted for nontermination of pregnancy and these patients had more obstetrical complications. The type of congenital anomaly and living children were the factors most associated with the choice for the termination of pregnancy.
Keywords Congenital Anomaly
Fetal Infeasibility
Maternal Risks
Termination Of PregnancyFetal Anomalies
Malformations
Diagnosis
Language English
Date 2016
Published in Journal Of Maternal-Fetal & Neonatal Medicine. Abingdon, v. 29, n. 23, p. 3762-3767, 2016.
ISSN 1476-7058 (Sherpa/Romeo, impact factor)
Publisher Wiley
Extent 3762-3767
Origin https://doi.org/10.3109/14767058.2016.1147557
Access rights Closed access
Type Article
Web of Science ID WOS:000384540600004
URI http://repositorio.unifesp.br/handle/11600/49393

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