Antireflux Surgery and Barrett's Esophagus: Myth or Reality?

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dc.contributor.author Herbella, Fernando Augusto Mardiros [UNIFESP]
dc.contributor.author Schlottmann, Francisco
dc.contributor.author Patti, Marco G.
dc.date.accessioned 2018-07-26T12:18:43Z
dc.date.available 2018-07-26T12:18:43Z
dc.date.issued 2018
dc.identifier http://dx.doi.org/10.1007/s00268-017-4394-8
dc.identifier.citation World Journal Of Surgery. New York, v. 42, n. 6, p. 1798-1802, 2018.
dc.identifier.issn 0364-2313
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/46015
dc.description.abstract It may seem questionable if antireflux surgery still has a role in the management of patients with Barrett's esophagus (BE) in the current era when antireflux surgery is facing a steady decline, obesity is increasing, pharmacologic treatment for gastroesophageal reflux disease (GERD) is in its splendor, and endoscopic techniques are used more frequently. It is questionable if patients with BE should be operated to stop GERD and to prevent cancer. The aim of this study was to determine the role of antireflux surgery in patients with BE. Literature review. The role of antireflux operations is, in fact, very controversial and neglected. BE is a different phenotype of GERD with a distinct pathophysiology linked to severe reflux of bile and acid, due to a marked anatomic disruption of the gastroesophageal barrier. Published series show that a fundoplication adequately controls GERD and symptoms in BE patients. A fundoplication (or even better a bile diversion antireflux procedure) may prevent esophageal adenocarcinoma. In conclusion, a fundoplication efficiently controls GERD and symptoms in BE patients. A fundoplication (or even better a bile diversion procedure) may also prevent esophageal adenocarcinoma. en
dc.format.extent 1798-1802
dc.language.iso eng
dc.publisher Springer
dc.rights Acesso restrito
dc.title Antireflux Surgery and Barrett's Esophagus: Myth or Reality? en
dc.type Artigo
dc.type Trabalho apresentado em evento
dc.description.affiliation Univ Fed Sao Paulo, Dept Surg, Escola Paulista Med, Rua Diogo de Faria 1087 Cj 301, BR-04037003 Sao Paulo, SP, Brazil
dc.description.affiliation Univ N Carolina, Dept Med, Chapel Hill, NC USA
dc.description.affiliation Univ N Carolina, Dept Surg, Chapel Hill, NC USA
dc.description.affiliationUnifesp Univ Fed Sao Paulo, Dept Surg, Escola Paulista Med, Rua Diogo de Faria 1087 Cj 301, BR-04037003 Sao Paulo, SP, Brazil
dc.identifier.doi 10.1007/s00268-017-4394-8
dc.description.source Web of Science
dc.identifier.wos WOS:000431425300030



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