Statins for progression of aortic valve stenosis and the best evidence for making decisions in health care

Statins for progression of aortic valve stenosis and the best evidence for making decisions in health care

Alternative title Estatinas para a progressão da estenose da valva aórtica e a melhor evidência para tomar decisões em saúde
Author Thiago, Luciana Google Scholar
Tsuji, Selma Rumiko Autor UNIFESP Google Scholar
Atallah, Alvaro Nagib Autor UNIFESP Google Scholar
Puga, Maria Eduarda dos Santos Autor UNIFESP Google Scholar
Gois, Aecio Flavio Teixeira de Autor UNIFESP Google Scholar
Institution Fac Med Marilia Famema
Universidade Federal de São Paulo (UNIFESP)
Brazilian Cochrane Ctr
Abstract In the Western world, calcified aortic valve stenosis is the most common form of valvular heart disease, affecting up to 3% of adults over the age of 75 years. It is a gradually progressive disease, characterized by a long asymptomatic phase that may last for several decades, followed by a short symptomatic phase associated with severe restriction of the valve orifice. Investigations on treatments for aortic valve stenosis are still in progress. Thus, it is believed that calcification of aortic valve stenosis is similar to the process of atherosclerosis that occurs in coronary artery disease. Recent studies have suggested that cholesterol lowering through the use of station may have a salutary effect on the progression of aortic valve stenosis.
Keywords Aortic valve stenosis
Hydroxymethylglutaryl-CoA reductase inhibitors
Atherosclerosis
Disease progression
Review [publication type]
Language English
Date 2011-01-06
Published in Sao Paulo Medical Journal. Sao Paulo: Associacao Paulista Medicina, v. 129, n. 1, p. 41-45, 2011.
ISSN 1516-3180 (Sherpa/Romeo, impact factor)
Publisher Associacao Paulista Medicina
Extent 41-45
Origin http://dx.doi.org/10.1590/S1516-31802011000100008
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000288620300008
SciELO ID S1516-31802011000100008 (statistics in SciELO)
URI http://repositorio.unifesp.br/11600/45552

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