Diffuse bone marrow metastasis in cerebellar high-grade astrocytoma. A case report

Diffuse bone marrow metastasis in cerebellar high-grade astrocytoma. A case report

Title: Diffuse bone marrow metastasis in cerebellar high-grade astrocytoma. A case report;
Metástasis difusa de la médula ósea en un astrocitoma cerebeloso de alto grado. Un caso clínico
Author Freitas, Marcelo Roberto Pereira Autor UNIFESP Google Scholar
Muzio, S. D. C. de Autor UNIFESP Google Scholar
Pessoa, R. C. C. Autor UNIFESP Google Scholar
Stávale, João Norberto Autor UNIFESP Google Scholar
Borges, Lia Raquel Rodrigues Autor UNIFESP Google Scholar
Malheiros, Suzana Maria Fleury Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract Introduction. Cerebellar high-grade astrocytoma is uncommon. Although more prone to present cerebrospinal fluid dissemination, the cerebellar location is not particularly related to the occurrence of extra-cranial metastases, which are also unusual in supratentorial malignant gliomas. Case report. A 46 year-old man with cerebellar anaplastic astrocytoma who developed pancytopenia due to extensive bone marrow metastases. Conclusion. Extraneural metastases of brain gliomas are rare and the spread to the bone marrow confers an extremely poor prognosis for these patients. The expected improvement in glioma patients' survival due to the combination of more efficient therapies may lead to an increased incidence of this uncommon presentation, justifying a more rigorous follow-up of systemic manifestations. [REV NEUROL 2009; 48: 242-4]
Keywords Anaplastic astrocytoma
Bone marrow metastases
Extraneural metastases
Gliomas
Malignant astrocytoma
Pancytopenia
Language Spanish
Date 2009-03-01
Published in Revista De Neurologia. Barcelona: Revista De Neurologia, v. 48, n. 5, p. 242-244, 2009.
ISSN 0210-0010 (Sherpa/Romeo, impact factor)
Publisher Revista De Neurologia
Extent 242-244
Origin http://www.neurologia.com/sec/resumen.php?or=web&i=e&id=2008202
Access rights Closed access
Type Article
Web of Science ID WOS:000264200200004
URI http://repositorio.unifesp.br/11600/45468

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