Trabeculectomy with mitomycin C in glaucoma associated with uveitis

Trabeculectomy with mitomycin C in glaucoma associated with uveitis

Author Prata Junior, João Antonio Autor UNIFESP Google Scholar
Neves, Renato Augusto Autor UNIFESP Google Scholar
Minckler, Donald S. Google Scholar
Mermoud, André Google Scholar
Heuer, Dale K. Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract Twenty-four trabeculectomies performed in 24 patients for control of uveitic galucoma were retrospectively evaluated to analyze the effect of intraoperative application of mitomycin C (MMC) on the short-term outcome of trabeculectomy for glaucoma associated with uveitis. Success rates, postoperative levels of intraocular pressure (IOP), and complications were studied. After a mean follow up of 9.87 months (range, 3 to 27 months), 18 eyes (75%) achieved an IOP of 21 mm Hg or less without antiglaucoma medications. The same IOP levels with one antiglaucoma medication was achieved in four eyes (16.6%). Statistical analysis demonstrated a significant reduction in IOP postoperatively during the period studied (P = .0001). Complications observed included exacerbation of the uveitis (12.5%), choroidal detachment (12.5%), hypotony (8.3%), postoperative shallow anterior chamber (4.2%), wound leak (4.2%), hyphema (4.2%), and macular edema (4.2%). The results of this retrospective and uncontrolled study suggest that intraoperative application of MMC may be a good option for enhancement of short-term trabeculectomy success rates in cases of uveitic glaucoma.
Language English
Date 1994-09-01
Published in Ophthalmic Surgery And Lasers. Thorofare: Slack Inc, v. 25, n. 9, p. 616-620, 1994.
ISSN 0022-023X (Sherpa/Romeo, impact factor)
Publisher Slack Inc
Extent 616-620
Access rights Closed access
Type Article
Web of Science ID WOS:A1994PN74900013

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