Cyclic alternating pattern as a sign of brain instability during sleep

Cyclic alternating pattern as a sign of brain instability during sleep

Author Ferre, A. Google Scholar
Guilleminault, Christian Google Scholar
Lopes, Maria Ceciclia Autor UNIFESP Google Scholar
Institution Hosp Valle De Hebron
Stanford Univ
Universidade Federal de São Paulo (UNIFESP)
Abstract During the last 20 years, the fact that the role of microarousal arousal is very involved in the pathophysiology of sleep disorders has been widely demonstrated. However, in spite of this, the nature of microarousal is still under debate. The awakening system forms a part of the relationship between activation system and sleep maintenance, thus providing the natural evolution of sleep and defending it from the stimuli of the external world. The awakening system, that includes the concept of microarousal, can appear isolated or periodically, then receiving the name of cyclic alternating pattern (CAP). CAP may be affected by different factors that can alter its periodicity, thus offering quantitative information on sleep instability. It can also serve as another new tool to understand human sleep and as complementary information supplied by the sleep macrostructure and microarousal study. This study aims to explain the concept of CAP and its pathophysiology studied up to the present.
Keywords microarousal
cyclic alternating pattern
Language Spanish
Date 2006-07-01
Published in Neurologia. Barcelona: S T M Editores, S A, v. 21, n. 6, p. 304-311, 2006.
ISSN 0213-4853 (Sherpa/Romeo, impact factor)
Publisher S T M Editores, S A
Extent 304-311
Access rights Closed access
Type Review
Web of Science ID WOS:000239387500005

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