LIGHT AND ELECTRON-MICROSCOPIC ANALYSIS OF INTRAOCULAR 2-PERCENT HYDROXYPROPYLMETHYLCELLULOSE

LIGHT AND ELECTRON-MICROSCOPIC ANALYSIS OF INTRAOCULAR 2-PERCENT HYDROXYPROPYLMETHYLCELLULOSE

Author Kwitko, Sérgio Autor UNIFESP Google Scholar
Belfort, Rubens Junior Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract Twenty samples of 2% hydroxypropylmethylcellulose for intraocular surgery, obtained from two Brazilian laboratories, were studied to determine the presence and type of impurities in the solutions. These were compared with ten samples of balanced salt solution (control group). Using light and scanning electron microscopy, five types of particles were identified: cellulose fibers, vegetable flakes, crystals, glass fragments, and other impurities. At least one of these contaminants was present in each sample of 2% hydroxypropylmethylcellulose. The vegetable matter was also seen in a sample of the raw material from which the clinical material had been prepared. Control solutions (i.e., balanced salt solution) were free of vegetable matter and of crystals, but glass fragments and other impurities were present. The average number of foreign particles in the solutions of hydroxypropylmethylcellulose (91.2 and 96.7 particles per milliliter for each of the two groups) was statistically greater than in the balanced salt solutions (13.7 particles per milliliter).
Keywords 2-PERCENT HYDROXYPROPYLMETHYLCELLULOSE
ENDOTHELIAL PROTECTION
VISCOELASTIC SUBSTANCE
Language English
Date 1991-07-01
Published in Journal Of Cataract And Refractive Surgery. Fairfax: Amer Soc Cataract Refractive Surgery, v. 17, n. 4, p. 478-484, 1991.
ISSN 0886-3350 (Sherpa/Romeo, impact factor)
Publisher Amer Soc Cataract Refractive Surgery
Extent 478-484
Origin http://dx.doi.org/10.1016/S0886-3350(13)80855-3
Access rights Closed access
Type Article
Web of Science ID WOS:A1991FW16900010
URI http://repositorio.unifesp.br/11600/44229

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