Dynamic hyperinflation during treadmill exercise testing in patients with moderate to severe COPD

Dynamic hyperinflation during treadmill exercise testing in patients with moderate to severe COPD

Alternative title Comportamento da hiperinsuflação dinâmica em teste em esteira rolante em pacientes com DPOC moderada a grave
Author Cordoni, Priscila Kessar Google Scholar
Berton, Danilo Cortozi Google Scholar
Squassoni, Selma Denis Google Scholar
Scuarcialupi, Maria Enedina Aquino Google Scholar
Neder, Jose Alberto Autor UNIFESP Google Scholar
Fiss, Elie Google Scholar
Institution Universidade Federal do ABC (UFABC)
Federacao Estabelecimentos Ensino Super Novo Hamb
Fac Med & Ciencias Med Paraiba
Universidade Federal de São Paulo (UNIFESP)
Abstract Objective: To characterize the presence, extent, and patterns of dynamic hyperinflation (DH) during treadmill exercise testing in patients with moderate to severe COPD. Methods: This was a cross-sectional study involving 30 non-hypoxemic patients (FEV1 = 43 +/- 14% of predicted) who were submitted to a cardiopulmonary exercise test on a treadmill at a constant speed (70-80% of maximum speed) to the tolerance limit (Tlim). Serial inspiratory capacity (1C) maneuvers were used in order to assess DH. Results: Of the 30 patients studied, 19 (63.3%) presented with OH (DH+ group), having greater pulmonary function impairment at rest than did those without UN (OH group). None of the variables studied correlated with exercise tolerance in the DH- group, whereas Tlim, 1C, and perception of dyspnea during exercise did so correlate in the DH+ group (p < 0.05). In the DH+ group, 7 and 12 patients, respectively, presented with a progressive and a stable pattern of DH (Delta 1C(Tlim,2min)= -0.28 +/- 0.11 L vs. 0.04 +/- 0.10 L; p <0.01). Patients with a progressive pattern of DH presented with higher perception of dyspnea/Tlim rate and lower exercise tolerance than did those with a stable pattern (354 +/- 118 s and 465 +/- 178 s, respectively; p < 0.05). Conclusions: The presence of DH is not a universal phenomenon during walking in COPD patients, even in those with moderate to severe airflow limitation. In the patients who presented DH, a progressive pattern of DH had a greater impact on exercise tolerance than did a stable pattern of DH.
Keywords Pulmonary disease, chronic obstructive
Exercise
Exercise test
Inspiratory capacity
Language Portuguese
Date 2012-01-01
Published in Jornal Brasileiro De Pneumologia. Brasilia Df: Soc Brasileira Pneumologia Tisiologia, v. 38, n. 1, p. 13-23, 2012.
ISSN 1806-3713 (Sherpa/Romeo, impact factor)
Publisher Soc Brasileira Pneumologia Tisiologia
Extent 13-23
Origin http://dx.doi.org/10.1590/S1806-37132012000100004
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000300651800004
SciELO ID S1806-37132012000100004 (statistics in SciELO)
URI http://repositorio.unifesp.br/11600/44156

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