Collection time of Thyroid hormones and TSH in preterm newborns

Collection time of Thyroid hormones and TSH in preterm newborns

Author Moraes, Simone Holzer de Google Scholar
Espiridião, Silvia Autor UNIFESP Google Scholar
Fonseca, Fernando Luiz Affonso Autor UNIFESP Google Scholar
Abreu, Luiz Carlos de Autor UNIFESP Google Scholar
Valenti, Vitor Engrácia Autor UNIFESP Google Scholar
Souto, Ricardo Peres do Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract Background: In this study we aimed to evaluate the collection time of T3, free T4 and TSH in preterm newborns.Methods: Prospective study, composed of 85 preterm newborns (PTI) as the gestational age stratified into four groups: Group A: n = 18 (less than 30 weeks); Group B: n = 13 (30 + 1 / 7-32 weeks); Group C: n = 19 (32 + 1 / 7 to 34 weeks) and; Group D: n = 35 (34 + 1 / 7 to 36 weeks). The collections of T3, T4 and thyroid stimulating hormone (TSH) were collected by chemiluminescence in six stages: 1 - umbilical cord; 2 - 3 days old; 3 - 7 days old; 4 - 14 days old; 5 - 30 days old and; 6 - 60 days old.Results: We observed significant differences until the dosage of 30 days, for free T4 between groups A and D; for the T3 between A and B groups with C and D groups. In the comparison between the times the time 1 was significantly different for TSH and T3.Conclusion: The hormone levels are gradually lower the lower the gestational age and the minimum ideal time for the collection of tests is from the 3(rd) day of life for TSH and the 7(th) day to the T4 and T3.
Keywords Thyroid Gland
Hormones
TSH (Thyroid Stimulating Hormone)
Infant
Newborn
Language English
Sponsor Nucleo de Estudos de Pesquisa da Faculdade de Medicina do ABC (NEPAS-FMABC)
Date 2011-01-01
Published in Healthmed. Sarajevo: Drunpp-sarajevo, v. 5, n. 3, p. 627-632, 2011.
ISSN 1840-2291 (Sherpa/Romeo, impact factor)
Publisher Drunpp-sarajevo
Extent 627-632
Access rights Closed access
Type Article
Web of Science ID WOS:000290567700024
URI http://repositorio.unifesp.br/11600/43757

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