Role of Physical Exercise as Complementary Treatment for Epilepsy and other Brain Disorders

Role of Physical Exercise as Complementary Treatment for Epilepsy and other Brain Disorders

Author Arida, Ricardo Mario Autor UNIFESP Google Scholar
Scorza, Fulvio Alexandre Autor UNIFESP Google Scholar
Cavalheiro, Esper Abrão Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract The impact of exercise on mental health, on cognition, brain function and brain structure as well as the possible underlying molecular systems important for maintaining neural function and plasticity has been extensively examined. Moreover, numerous studies have reinforced t the important and beneficial role of exercise for those with neurological disorders. This article reviews general aspects of physical exercise against neurodegenerative diseases and the relevant contributions of physical exercise programs as complementary therapy for epilepsy. We first give an overview of the plasticity induced by exercise in the damaged brain, the impact of exercise in reducing brain injury as well as in delaying onset of and decline in several neurodegenerative diseases. We address the relationship between epilepsy and exercise and report the neuroprotective and antiepileptogenic effects of exercise on epilepsy based on experimental and clinical studies. Overall, we conclude that physical or sport activities represent an exciting intervention that should be integrated with conventional therapy for the improvement of brain function and resistance to neurodegenerative diseases as well as a complementary non-pharmacological treatment of epilepsy.
Keywords Physical activity
exercise
brain injury
neurodegenerative diseases
epilepsy
seizure
neuroprotection
Language English
Sponsor Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
INNT (Brazil)
Date 2013-11-01
Published in Current Pharmaceutical Design. Sharjah: Bentham Science Publ Ltd, v. 19, n. 38, p. 6720-6725, 2013.
ISSN 1381-6128 (Sherpa/Romeo, impact factor)
Publisher Bentham Science Publ Ltd
Extent 6720-6725
Origin http://dx.doi.org/10.2174/1381612811319380004
Access rights Closed access
Type Article
Web of Science ID WOS:000326344600004
URI http://repositorio.unifesp.br/11600/43468

Show full item record




File

File Size Format View

There are no files associated with this item.

This item appears in the following Collection(s)

Search


Browse

Statistics

My Account