Postoperative subconjunctival corticosteroid injection to prevent pterygium recurrence

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dc.contributor.author Paris, Fabiana dos Santos [UNIFESP]
dc.contributor.author Farias, Charles Costa de [UNIFESP]
dc.contributor.author Melo, Gustavo Barreto de [UNIFESP]
dc.contributor.author Santos, Myrna Serapião dos [UNIFESP]
dc.contributor.author Batista, Jefferson Luiz Alves [UNIFESP]
dc.contributor.author Gomes, José Álvaro Pereira [UNIFESP]
dc.date.accessioned 2018-06-15T17:05:09Z
dc.date.available 2018-06-15T17:05:09Z
dc.date.issued 2008-05-01
dc.identifier https://dx.doi.org/10.1097/ICO.0b013e318162af90
dc.identifier.citation Cornea. Philadelphia: Lippincott Williams & Wilkins, v. 27, n. 4, p. 406-410, 2008.
dc.identifier.issn 0277-3740
dc.identifier.uri http://repositorio.unifesp.br/11600/43422
dc.description.abstract Purpose: To report the outcome of postoperative subconjunctival injection of triamcinolone in eyes that underwent pterygium surgery and were at risk for recurrence.Methods: Twelve eyes of 11 patients with primary (7 eyes) or recurrent (5 eyes) pterygia underwent excision and conjunctival autografting (4 eyes, 33.3%), an-miotic membrane grafting (6 eyes, 50%), or both (2 eyes, 16.6%). All of these eyes had signs that were considered to be risk factors for recurrence (conjunctival inflammation, hemorrhage, granuloma, and fibrovascular proliferation); accordingly, they also underwent subconjunctival injection of triamcinolone.Results: Among the 11 patients, there were 8 (72.7%) men and 3 (27.3%) women; the mean age was 41 years (range, 20 - 56 years). In 5 (41.7%) eyes, the pterygium was graded as T2 (intermediate) and in 7 (58.3%) eyes was graded as T3 (fleshy). The time between surgery and the first injection ranged from 2 to 5 weeks (mean, 3.4 weeks), and 1 - 3 injections were necessary (mean, 1.7) to achieve the desired effect. After injection, 1 (8.3%) eye developed inflammation, and 2 (16.7%) eyes from another patient developed intraocular hypertension that was controlled with a topical P-blocker. The follow-up after the last injection ranged from 8 to 36 months (mean, 14.5 months); only 1 recurrence (grade 3) occurred during this period.Conclusions: The postoperative use of subconjunctival triamcinclone seems to benefit patients at increased risk of pterygium recurrence. It is relatively safe and is accompanied by few complications, but controlled and prospective studies are necessary to confirm its efficacy. en
dc.format.extent 406-410
dc.language.iso eng
dc.publisher Lippincott Williams & Wilkins
dc.relation.ispartof Cornea
dc.rights Acesso restrito
dc.subject pterygium en
dc.subject corticosteroids en
dc.subject subconjunctiva en
dc.subject recurrence en
dc.title Postoperative subconjunctival corticosteroid injection to prevent pterygium recurrence en
dc.type Artigo
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.description.affiliation Univ Fed Sao Paulo, Dept Ophthalmol, External Dis & Cornea Serv, BR-04023062 Sao Paulo, Brazil
dc.description.affiliationUnifesp Univ Fed Sao Paulo, Dept Ophthalmol, External Dis & Cornea Serv, BR-04023062 Sao Paulo, Brazil
dc.identifier.doi 10.1097/ICO.0b013e318162af90
dc.description.source Web of Science
dc.identifier.wos WOS:000255470600004



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