Postoperative subconjunctival corticosteroid injection to prevent pterygium recurrence

Postoperative subconjunctival corticosteroid injection to prevent pterygium recurrence

Author Paris, Fabiana dos Santos Autor UNIFESP Google Scholar
Farias, Charles Costa de Autor UNIFESP Google Scholar
Melo, Gustavo Barreto de Autor UNIFESP Google Scholar
Santos, Myrna Serapião dos Autor UNIFESP Google Scholar
Batista, Jefferson Luiz Alves Autor UNIFESP Google Scholar
Gomes, José Álvaro Pereira Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract Purpose: To report the outcome of postoperative subconjunctival injection of triamcinolone in eyes that underwent pterygium surgery and were at risk for recurrence.Methods: Twelve eyes of 11 patients with primary (7 eyes) or recurrent (5 eyes) pterygia underwent excision and conjunctival autografting (4 eyes, 33.3%), an-miotic membrane grafting (6 eyes, 50%), or both (2 eyes, 16.6%). All of these eyes had signs that were considered to be risk factors for recurrence (conjunctival inflammation, hemorrhage, granuloma, and fibrovascular proliferation); accordingly, they also underwent subconjunctival injection of triamcinolone.Results: Among the 11 patients, there were 8 (72.7%) men and 3 (27.3%) women; the mean age was 41 years (range, 20 - 56 years). In 5 (41.7%) eyes, the pterygium was graded as T2 (intermediate) and in 7 (58.3%) eyes was graded as T3 (fleshy). The time between surgery and the first injection ranged from 2 to 5 weeks (mean, 3.4 weeks), and 1 - 3 injections were necessary (mean, 1.7) to achieve the desired effect. After injection, 1 (8.3%) eye developed inflammation, and 2 (16.7%) eyes from another patient developed intraocular hypertension that was controlled with a topical P-blocker. The follow-up after the last injection ranged from 8 to 36 months (mean, 14.5 months); only 1 recurrence (grade 3) occurred during this period.Conclusions: The postoperative use of subconjunctival triamcinclone seems to benefit patients at increased risk of pterygium recurrence. It is relatively safe and is accompanied by few complications, but controlled and prospective studies are necessary to confirm its efficacy.
Keywords pterygium
corticosteroids
subconjunctiva
recurrence
Language English
Date 2008-05-01
Published in Cornea. Philadelphia: Lippincott Williams & Wilkins, v. 27, n. 4, p. 406-410, 2008.
ISSN 0277-3740 (Sherpa/Romeo, impact factor)
Publisher Lippincott Williams & Wilkins
Extent 406-410
Origin https://dx.doi.org/10.1097/ICO.0b013e318162af90
Access rights Closed access
Type Article
Web of Science ID WOS:000255470600004
URI http://repositorio.unifesp.br/11600/43422

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