Zinc, copper and iron and their interrelations in the growth of sickle cell patients

Zinc, copper and iron and their interrelations in the growth of sickle cell patients

Author Braga, Josefina Aparecida Pellegrini Autor UNIFESP Google Scholar
Kerbauy, José Autor UNIFESP Google Scholar
Fisberg, Mauro Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract In this study we evaluated the nutritional status of 34 children with sickle cell disease (SS). Results were compared to 9 siblings with sickle cell trait (AS) and 35 eutrophic children who presented normal hemoglobin and normal hemoglobin electrophoresis (AA). All of then came from low socioeconomic level.Analysis of the growth velocity curves revelead in SS group, tendency to increase deficit in weight and height with age. There was no relation between weight/height (W/H) and height/age (H/A) percentile and hemoglobin levels. There was no significant relation between nutritional status and severity of the disease. SS group showed significant skeletal maturation delay, the same did not occur with the siblings (AS group).Plasma zinc levels were significantly lower in SS group than in AS and AA groups In SS group there was some association between lower plasma zinc levels and WA percentile lower or equal to 10. Plasma copper levels were significantly greater in SS group than in AS and AA ones, and then was no relation between plasma copper levels and serum ferritin levels.In conclusion, our patients with sickle cell disease showed indexes of malnutrition, iron deficiency, hipercupremia and low plasma zinc levels related to low stature.
Language English
Date 1995-09-01
Published in Archivos Latinoamericanos De Nutricion. Caracas: Archivos Latinoamericanos Nutricion, v. 45, n. 3, p. 198-203, 1995.
ISSN 0004-0622 (Sherpa/Romeo, impact factor)
Publisher Archivos Latinoamericanos Nutricion
Extent 198-203
Access rights Closed access
Type Article
Web of Science ID WOS:A1995UA97100007
URI http://repositorio.unifesp.br/11600/42677

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