Low level laser therapy (AlGaInP) applied at 5J/cm(2) reduces the proliferation of Staphylococcus aureus MRSA in infected wounds and intact skin of rats

Low level laser therapy (AlGaInP) applied at 5J/cm(2) reduces the proliferation of Staphylococcus aureus MRSA in infected wounds and intact skin of rats

Alternative title Laser de baixa intensidade (AlGaInP) aplicado com 5J/cm2 reduz a proliferação de Staphilococcus aureus MRSA em feridas infectadas e em pele íntegra de ratos
Author Silva, Daniela Conceicao Gomes Goncalves Autor UNIFESP Google Scholar
Plapler, Helio Autor UNIFESP Google Scholar
Costa, Mateus Matiuzzi da Google Scholar
Silva, Silvio Romero Gonçalves e Autor UNIFESP Google Scholar
Sa, Maria da Conceicao Aquino de Google Scholar
Silva, Benedito Savio de Lima e Autor UNIFESP Google Scholar
Institution Fac Inspirar Petrolina
Universidade Federal de São Paulo (UNIFESP)
Natl Inst Med Care & Social Welf INAMPS
Universidade Federal de Sergipe (UFS)
Fed Univ Vale do Sao Francisco Fdn UNIVASF
Abstract BACKGROUND: Laser therapy is a low cost, non-invasive procedure with good healing results. Doubts exist as to whether laser therapy action on microorganisms can justify research aimed at investigating its possible effects on bacteria-infected wounds.OBJECTIVE: To assess the effect of low intensity laser on the rate of bacterial contamination in infected wounds in the skin of rats.METHODS: An experimental study using 56 male Wistar rats. The animals were randomly divided into eight groups of seven each. Those in the infected groups were infected by Staphylococcus aureus MRSA in the dorsal region. Red laser diode (AlGaInP) 658nm, 5J/cm(2) was used to treat the animals in the treated groups in scan for 3 consecutive days. Samples were drawn before inoculating bacteria and following laser treatment. For statistical analysis we used the nonparametric Wilcoxon (paired data) method with a significance level of p < 0.05.RESULTS: The statistical analysis of median values showed that the groups submitted to laser treatment had low bacterial proliferation.CONCLUSION: The laser (AlGaInP), with a dose of 5J/cm(2) in both intact skin and in wounds of rats infected with Staphylococcus aureus MRSA, is shown to reduce bacterial proliferation.
Keywords Bacterial infections
Laser therapy, low-level
Surgical wound infection
Language English
Date 2013-01-01
Published in Anais Brasileiros De Dermatologia. Rio De Janeiro Rj: Soc Brasileira Dermatologia, v. 88, n. 1, p. 50-55, 2013.
ISSN 0365-0596 (Sherpa/Romeo, impact factor)
Publisher Soc Brasileira Dermatologia
Extent 50-55
Origin http://dx.doi.org/10.1590/S0365-05962013000100005
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000316807000005
SciELO ID S0365-05962013000100005 (statistics in SciELO)
URI http://repositorio.unifesp.br/11600/42509

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