Determination of splenomegaly by CT: Is there a place for a single measurement?

Determination of splenomegaly by CT: Is there a place for a single measurement?

Author Bezerra, Alexandre S. Google Scholar
D'Ippolito, Giuseppe Autor UNIFESP Google Scholar
Faintuch, Salomão Autor UNIFESP Google Scholar
Szejnfeld, Jacob Autor UNIFESP Google Scholar
Ahmed, Muneeb Google Scholar
Institution Univ Catolica Brasilia
Universidade Federal de São Paulo (UNIFESP)
Harvard Univ
Abstract OBJECTIVE. Our objective was to determine if there is a single parameter that can be used as a marker of splenomegaly using CT.MATERIALS AND METHODS. Splenic length, width, and thickness were measured in 249 CT scans and multidimensional indexes were obtained from the multiplication of these measurements. Volume was calculated by summing the volumes of multiple contiguous scans. The relationship of the spleen to the left liver lobe and inferior third of the left kidney was also evaluated. Linear equations were obtained to correlate each measurement to the splenic volume.RESULTS. The unidimensional measurements with best correlation to volume were splenic length (r = 0.8 1, p < 0.01) and width (r = 0.804, p < 0.0 1). Correlation was better for the multidimensional indexes (r = 0.95, p < 0.0 1). Using a previously described upper limit of normality for splenic volume of 314.5 cm(3) in the linear regression equation obtained, a maximum spleen length of 9.76 cm was the upper limit of normality. The relation of the lowest point of the spleen to the inferior third of the kidney also showed that if the spleen reached or extended below this portion of the kidney, it could be used as evidence of splenomegaly (p < 0.005), although it had a low sensitivity.CONCLUSION. Splenic length and multidimensional indexes correlate well with splenic CT volume. A splenic length of 9.76 cm can be used to accurately diagnose splenomegaly and can replace multiple-measurement, time-consuming methods in the clinical routine.
Language English
Date 2005-05-01
Published in American Journal Of Roentgenology. Reston: Amer Roentgen Ray Soc, v. 184, n. 5, p. 1510-1513, 2005.
ISSN 0361-803X (Sherpa/Romeo, impact factor)
Publisher Amer Roentgen Ray Soc
Extent 1510-1513
Origin http://dx.doi.org/10.2214/ajr.184.5.01841510
Access rights Closed access
Type Article
Web of Science ID WOS:000228875300025
URI http://repositorio.unifesp.br/11600/42398

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