Sensitisation to aeroallergens in Brazilian adolescents living at the periphery of large subtropical urban centres

Sensitisation to aeroallergens in Brazilian adolescents living at the periphery of large subtropical urban centres

Author Pastorino, Antonio Carlos Google Scholar
Kuschnir, Fabio Chigres Google Scholar
Arruda, Luisa Karla de Paula Autor UNIFESP Google Scholar
Casagrande, Rejane Rimazza Dalberto Google Scholar
Souza, Renata Gontijo Lima de Google Scholar
Dias, Gabriela Andrade Coelho Google Scholar
Silveira, H. H. N. Google Scholar
Cunha, Antonio Jose Ledo Alves da Google Scholar
Jacob, Cristina Miuki Abe Autor UNIFESP Google Scholar
Solé, Dirceu Autor UNIFESP Google Scholar
Institution Universidade de São Paulo (USP)
Universidade Federal do Rio de Janeiro (UFRJ)
Secretariet Civil Def
Universidade Federal de São Paulo (UNIFESP)
Abstract Objectives: To evaluate the sensitization to aeroallergens determined by skin prick test (SPT) in Brazilian adolescents, and to correlate its positivity with the diagnosis of asthma and/or rhinitis based on the written questionnaire (WQ) of ISAAC phase III study.Patients and Methods: A total of 996 adolescents (387 boys) were selected by systematic samples. A standard allergen extracts panel (positive/negative control, D pteronyssinus [Dpt], P americana [Pal, B germanica [Bg], dog, cat, fungal and grass mix) was used and its positivity compared with positive responses to asthma, rhinitis or both.Results: Positive SPT to at least one allergen was observed in 466 adolescents (46.8 %), with sensitisation to Dpt in 79.1 %. Positivity to more than one allergen occurred in 232 students (49.8 %). The frequency of positive SPTs was significantly higher among adolescents with asthma (OR = 2.16), rhinitis (OR = 1.69), and asthma and rhinitis (OR = 2.03). Positive SPT to four or more allergens were higher among asthmatics (OR = 2.6) and among adolescents with asthma and rhinitis (OR = 3).Conclusions: A high sensitisation rate to aeroallergens was observed, significantly higher among those with asthma, rhinitis or a combination of both, especially in multiple sensitisations.
Keywords atopy
skin prick test
risk factor
Language English
Date 2008-01-01
Published in Allergologia Et Immunopathologia. Barcelona: Elsevier Doyma Sl, v. 36, n. 1, p. 9-16, 2008.
ISSN 0301-0546 (Sherpa/Romeo, impact factor)
Publisher Elsevier B.V.
Extent 9-16
Access rights Closed access
Type Article
Web of Science ID WOS:000254251200003

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