Trypanosoma cruzi meningoencephalitis in AIDS mimicking cerebral metastases: case report

Trypanosoma cruzi meningoencephalitis in AIDS mimicking cerebral metastases: case report

Alternative title Meningoencefalite chagásica em AIDS simulando metástases cerebrais: relato de caso
Author Pimentel, Pedro Camilo A. Autor UNIFESP Google Scholar
Handfas, Benjamin W. Google Scholar
Carmignani, Márcia Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Hospital Albert Einstein Division of Neuroimaging
Abstract A case of Chagas' meningoencephalitis in a 47 year-old patient with AIDS is presented. The diagnosis was established by examination of the cerebrospinal fluid which showed the presence of Trypanosoma cruzi. CT-scan revealed multiple cerebral lesions which only became evident by contrast administration. A second CT after 13 days showed a severe evolution with displacement of the midline structures leading to the patient's death. This case, as well as other case reports published, has shown the fulminant evolution of Chagas' meningoencephalitis in AIDS patients and the importance of cerebrospinal fluid examination for the diagnosis.

Apresentamos um caso de meningoencefalite chagásica em paciente de 47 anos com AIDS. O diagnóstico foi feito pelo encontro do Trypanosoma cruzi no LCR. A tomografia de crânio mostrou múltiplas lesões cerebrais que se tornaram evidentes apenas na fase com contraste. Uma segunda tomografia após 13 dias mostrou evolução tipo tumoral com intenso efeito de massa e acentuado desvio de estruturas da linha média, levando o paciente ao óbito. Este caso e outros da literatura mostram a evolução fulminante da meningoencefalite chagásica em pacientes com AIDS e a importância do exame de LCR para o diagnóstico.
Keywords cerebral metastases
encephalitis
Chagas' disease
Trypanosoma cruzi
AIDS
metastases cerebrais
encefalite
doença de Chagas
Trypanosoma cruzi
AIDS
Language English
Date 1996-03-01
Published in Arquivos de Neuro-Psiquiatria. Academia Brasileira de Neurologia - ABNEURO, v. 54, n. 1, p. 102-106, 1996.
ISSN 0004-282X (Sherpa/Romeo, impact factor)
Publisher Academia Brasileira de Neurologia - ABNEURO
Extent 102-106
Origin http://dx.doi.org/10.1590/S0004-282X1996000100017
Access rights Open access Open Access
Type Article
Web of Science ID WOS:A1996TZ93500017
SciELO ID S0004-282X1996000100017 (statistics in SciELO)
URI http://repositorio.unifesp.br/handle/11600/411

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