Magnetic resonance imaging-guided occult breast lesion localization and simultaneous sentinel lymph node mapping

Magnetic resonance imaging-guided occult breast lesion localization and simultaneous sentinel lymph node mapping

Author Docema, Marcos Fernando de Lima Google Scholar
Costa, Paulo Aguirre Google Scholar
Andrade, Felipe Eduardo Martins de Google Scholar
Bevilacqua, Jose Luiz Barbosa Google Scholar
Elias, Simone Autor UNIFESP Google Scholar
Cerri, Giovanni Guido Google Scholar
Barros, Alfredo Carlos S. D. Google Scholar
Nazario, Afonso Celso Pinto Autor UNIFESP Google Scholar
Institution Hosp Sirio Libanes
Universidade Federal de São Paulo (UNIFESP)
Abstract Background: Radio-guided occult lesion localization is a valid technique for the diagnosis of suspicious non-palpable lesions. Here we determine the feasibility of pre-operative localization of occult suspect non-palpable breast lesions using radio-guided occult lesion localization, as well as for identifying the sentinel lymph node.Methods: This is a descriptive study of data collected retrospectively. Pre-operative mapping of 34 breast lesions in 25 patients suspected of being malignant was performed using conventional imaging methods with a magnetic resonance imaging-guided radiopharmaceutical injection.Results: the mean time required to perform the localization was 25 minutes. After resection of the lesions using a gamma probe, malignancy was confirmed in fifteen patients (60.0%), with nine invasive ductal carcinomas, two invasive lobular carcinomas, and four in situ ductal carcinomas the resection was confirmed by the complete removal of the radioactive material. the pathologic results and images were concordant in all but two cases, which were submitted for new magnetic resonance imaging examinations and surgery that confirmed the malignancies. of the 15 patients with confirmed malignancies, 10 had sentinel lymph node resection. of these, eight were negative for metastases, one had micro-metastases and one had confirmed metastases. Three patients had full axillary node dissection, with metastases found in only one. No side effects were observed with magnetic resonance-guided radiopharmaceutical injection.Conclusions: the sentinel node occult lesion localization technique is a simple, reproducible and effective alternative approach to occult lesions compared to other methods, such as mammotomy and the hook-wire localization technique, for mapping suspect breast lesions and identifying lymph node metastasis.
Language English
Date 2014-10-23
Published in World Journal of Surgical Oncology. London: Biomed Central Ltd, v. 12, 9 p., 2014.
ISSN 1477-7819 (Sherpa/Romeo, impact factor)
Publisher Biomed Central Ltd
Extent 9
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000344847700001

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