Safety assessment of cosmetic products, with emphasis on the ocular area: regulatory aspects and validation processes

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dc.contributor.author Cancian, Maythe de Lima [UNIFESP]
dc.contributor.author Leonardi, Mauricio Saadi
dc.contributor.author Mosca, Mariane Martins
dc.contributor.author Guerra, Lucas Offenbecker
dc.contributor.author Hengeltraub, Simone Fanan
dc.contributor.author Leonardi, Gislaine Ricci [UNIFESP]
dc.date.accessioned 2016-01-24T14:37:54Z
dc.date.available 2016-01-24T14:37:54Z
dc.date.issued 2014-10-01
dc.identifier http://dx.doi.org/10.1590/S1984-82502014000400002
dc.identifier.citation Brazilian Journal of Pharmaceutical Sciences. São Paulo: Univ São Paulo, Conjunto Quimicas, v. 50, n. 4, p. 667-676, 2014.
dc.identifier.issn 1984-8250
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/38256
dc.description.abstract Before marketing a cosmetic product, a series of biological assays, such as ocular irritation tests, must be conducted in order to prove that the product is safe. However, a few scientific articles mention the discussion and evolution of cosmetic products testing performed in the eyes area. the aim of this study was to review the available literature on the evolution of tests carried out with cosmetics, in the ocular area, as well as to describe the methodologies that have been used and that are currently accepted. in Brazil, tests performed on animals are still allowed. However, the international laws strongly recommend the use of alternative methods for evaluating the risk of cosmetic ingredients and products. Regulatory requirements involving the registration of these products also request safety support of them in human beings. To perform ocular tests in human beings, it is necessary to involve an ophthalmologist for conducting clinical protocols. These protocols signed by the expert physician are sent to the National Health Surveillance Agency in order to endorse the product manufacturer concerning its safety. the safety support of a cosmetic product is very important, taking into account that the consumer has free access to these products of widespread use in today's society. en
dc.format.extent 667-676
dc.language.iso eng
dc.publisher Univ São Paulo, Conjunto Quimicas
dc.relation.ispartof Brazilian Journal of Pharmaceutical Sciences
dc.rights Acesso aberto
dc.subject Eyes/cosmetics use en
dc.subject Cosmetics/safety assessment en
dc.subject Ocular irritation/tests en
dc.subject Ocular area/safety use of cosmetics en
dc.title Safety assessment of cosmetic products, with emphasis on the ocular area: regulatory aspects and validation processes en
dc.type Resenha
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.contributor.institution Grp Invest
dc.contributor.institution TRIDSKIN Labs Ltda
dc.description.affiliation Universidade Federal de São Paulo, Inst Environm Chem & Pharmaceut Sci, BR-09913030 Diadema, SP, Brazil
dc.description.affiliation Universidade Federal de São Paulo, Dept Med, São Paulo, SP, Brazil
dc.description.affiliation Grp Invest, Campinas, SP, Brazil
dc.description.affiliation TRIDSKIN Labs Ltda, Grp Invest, Campinas, SP, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Inst Environm Chem & Pharmaceut Sci, BR-09913030 Diadema, SP, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Dept Med, São Paulo, SP, Brazil
dc.identifier.scielo S1984-82502014000400002
dc.identifier.doi 10.1590/S1984-82502014000400002
dc.description.source Web of Science
dc.identifier.wos WOS:000350869000002



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