Functional capacity after pediatric liver transplantation: A pilot study

Functional capacity after pediatric liver transplantation: A pilot study

Author Silva, Rosangela Maria da Autor UNIFESP Google Scholar
Carvalho, Werther Brunow de Google Scholar
Johnston, Cintia Autor UNIFESP Google Scholar
Castro, Mariela Borba de Autor UNIFESP Google Scholar
Ferreira, Israel Manta Autor UNIFESP Google Scholar
Patti, Camilla L. Autor UNIFESP Google Scholar
Azevedo, Ramiro Anthero de Autor UNIFESP Google Scholar
Gonzalez, Adriano Miziara Autor UNIFESP Google Scholar
Linhares, Marcelo Moura Autor UNIFESP Google Scholar
Salzedas-Netto, Alcides Augusto Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Universidade de São Paulo (USP)
Abstract The prospective cross-sectional study investigated the 6MWT performance in pediatric group of liver transplant recipients (6-17 yr, median post-transplantation time of 22 months) and compared to the normal values obtained in healthy children as well as evaluated the reproducibility of the 6MWT. We analyzed the relationship between walked distance and the 6MWw, distance walked x body weight) with the anthropometric, clinical, and pulmonary functions. in post-transplanted group, the average walked distance was significantly shorter compared with control (687 +/- 80 m vs. 511 +/- 72 m, p < 0.001). the calculated ICC coefficient confirmed the reproducibility among tests. the Pearson correlation revealed that only walked distance in the 6MWT was moderately correlated with tidal volume. Conversely, the 6MWw was significantly correlated with age, weight, height, BMI, FVC, PEF rate, and volume expiratory. According to multiple regression analysis, age, VE and FVC factors explained 80% of the variance in the 6MWw. in conclusion, the pediatric liver transplant recipients' performance in the 6MWT is significantly lower than the values for healthy children of the same age. Notably, the 6MWw may provide relevant information, constituting an additional parameter in the determination of functional capacity.
Keywords liver transplantation
stress test
physical fitness
six-min walk test
Language English
Date 2014-09-01
Published in Pediatric Transplantation. Hoboken: Wiley-Blackwell, v. 18, n. 6, p. 586-593, 2014.
ISSN 1397-3142 (Sherpa/Romeo, impact factor)
Publisher Wiley-Blackwell
Extent 586-593
Access rights Closed access
Type Article
Web of Science ID WOS:000340530800014

Show full item record


File Size Format View

There are no files associated with this item.

This item appears in the following Collection(s)




My Account