Antiretroviral treatment adherence in childhood and adolescence: Multidisciplinary team as an associated factor in Brazil

Antiretroviral treatment adherence in childhood and adolescence: Multidisciplinary team as an associated factor in Brazil

Author Crozatti, Marcia Terezinha Lonardoni Autor UNIFESP Google Scholar
Franca-Junior, Ivan Google Scholar
Rodrigues, Rosangela Google Scholar
Ferrao, Maria do Socorro Carneiro Google Scholar
Brigido, Luis Fernando M. Google Scholar
Negra, Marinella Della Google Scholar
Campeas, Alexandre Ely Google Scholar
Raymundo, Miriam Elia Castilho Google Scholar
Marques, Silvia Regina Google Scholar
Waldman, Eliseu Alves Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Universidade de São Paulo (USP)
Adolfo Lutz Inst
Emilio Ribas Inst Infectol
Abstract Our aim was to analyze factors associated with non-adherence to antiretroviral (ARV) treatment among children and adolescents. A cross-sectional study was carried out involving non-institutionalized children and adolescents between 2 and 20 years of age, addressing non-adherence to ARV treatment, which was defined as taking 89% of the medications on the day of the interview and the three previous days. the investigation into the association between non-compliance and the variables of interest was performed using unconditional logistic regression. the independent factors associated with non-adherence were forgetfulness (OR = 3.22; 95%CI = 1.75-5.92), difficulties coping with treatment (OR = 2.65; 95%CI = 1.03-6.79), and living with grandparents (OR = 2.28; 95%CI = 1.08-4.83), whereas a protective effect was found with participation in multidisciplinary activities (OR = 0.49; 95%CI = 0.25-0.96), i.e., this factor indicates that the exposure to the variable is beneficial, promoting adherence. We concluded that forgetting to take the medications and reporting having difficulty coping with ARV treatment are potentially modifiable factors through educational and programmatic actions. Residing with one's grandparents may strongly impact adherence to ARV treatment, indicating the need for the systematic support of these family members. Participation in multidisciplinary activities should be stimulated at health-care services.
Keywords antiretroviral therapies
medication adherence
Language English
Date 2013-11-01
Published in Aids Care-psychological and Socio-medical Aspects of Aids/hiv. Abingdon: Routledge Journals, Taylor & Francis Ltd, v. 25, n. 11, p. 1462-1469, 2013.
ISSN 0954-0121 (Sherpa/Romeo, impact factor)
Publisher Routledge Journals, Taylor & Francis Ltd
Extent 1462-1469
Access rights Closed access
Type Article
Web of Science ID WOS:000326370900018

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